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1.C.112.1.1
Cubozoan toxin, CaTX-A of 463 aas.  This toxin has potent hemolytic activity, is lethal to crayfish. causes cutaneous inflammation in humans, and may act as a pore-forming toxin, disrupting normal transmembrane ion concentration gradients in susceptible cells (Nagai et al. 2000; Brinkman and Burnell 2009).

Accession Number:Q9GNN8
Protein Name:Toxin CaTX-A
Length:463
Molecular Weight:51605.00
Species:Carybdea alata (Hawaiian box jellyfish) [112899]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Secreted1
Substrate ions

Cross database links:

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  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSRGYSLHLV LFLVLSTAFP SQARLSRYRR SAADAVSTDI DGIIGQLNDL GTDTKRLKEA 
61:	LQGVQEAVKK EPATTIAKVS TIVGSVGGSL SKFKSGDPFD VASGCLDIIA SVATTFGGPY 
121:	GIAIGAVASL ISSILSLFSG NSMGSAIKQV IDDAFKKYRD QELEDNVKGA KRTFNAVITF 
181:	VNSVSKTENL TEVHLDSVRD AVRVDAFTNM LGVLESRINR GSVSTDNNEA MRTINFIFLY 
241:	LQLSVMRETL LTQVILLYKR AGGAYDELAL SLSLTSDQNK EATRETVTFL HQMETKYSLC 
301:	GSYYYPIDHS KAAIGILKLT KFFGVPDPAR YTFDGLYYRM QNRAWNRYSI CKESYAGNHM 
361:	FRGCKDSSYH GIRIKKLENG YHTITLRSKA MYVTKHAQGW GWGTADEDPG EQGYFTFIPL 
421:	TNGFYMVSTK KWPDYFVYME SSAHGYIRSW HYNPDPQGQW KIL