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1.C.113.2.3
Progestin and adipoQ receptor family member 10, PAQR10, of 270 aas and 7 TMSs.  Also called Monocyte to macrophage differentiation factor 2, MMD2. PAQR10 is structurally related to some bacterial hemolysins, pore-forming virulence factors that target mitochondria and regulate apoptosis (Góñez et al. 2008).

Accession Number:Q8IY49
Protein Name:Monocyte to macrophage differentiation factor 2
Length:270
Molecular Weight:31264.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Golgi apparatus membrane1 / Multi-pass membrane protein2
Substrate small molecules

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MFAPRLLDFQ KTKYARFMNH RVPAHKRYQP TEYEHAANCA THAFWIIPSI LGSSNLYFLS 
61:	DDDWETISAW IYGLGLCGLF VVSTVFHTIS WKKSHLRMVE HCLHMFDRMV IYFFIAASYA 
121:	PWLNLRELGP WASHMRWLVW IMASVGTIYV FFFHERTGSC VQFLRGEACP KAGTACLPAR 
181:	YKLVELLCYV VMGFFPALVI LSMPNTEGIW ELVTGGVFYC LGMVFFKSDG RIPFAHAIWH 
241:	LFVAFGAGTH YYAIWRYLYL PSTLQTKVSK