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1.C.12.1.3
Cereolysin O (hemolysin I) (Ramarao and Sanchis 2013).

Accession Number:Q815P0
Protein Name:Perfringolysin O
Length:512
Molecular Weight:56596.00
Species:Bacillus cereus [226900]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Secreted1
Substrate small molecules, large molecules

Cross database links:

eggNOG: NOG04845
HEGENOM: HBG337470
RefSeq: NP_834769.1   
Entrez Gene ID: 1207442   
Pfam: PF01289   
BioCyc: BCER226900:BC_5101-MONOMER   
KEGG: bce:BC5101   

Gene Ontology

GO:0015485 F:cholesterol binding
GO:0009405 P:pathogenesis

References (1)

[1] “Genome sequence of Bacillus cereus and comparative analysis with Bacillus anthracis.”  Ivanova N.et.al.   12721630

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MIFLNIKKNT KRRKFLACLL VSLCTINYSS ISFAETQASN ATDVTKNASG IDTGIANLKY 
61:	NNQEVLAVNG DKIESFVPKE SINSNGKFVV VEREKKSLTT SPVDISIIDS VVNRTYPGAV 
121:	QLANKAFADN QPSLLVAKRK PLNISIDLPG MRKENTITVQ NPTYGNVAGA VDDLVSTWNE 
181:	KYSTTHTLPA RMQYTESMVY SKSQIASALN VNAKYLDNSL NIDFNAVANG EKKVMVAAYK 
241:	QIFYTVSAEL PNNPSDLFDN SVTFDELTRK GVSNSAPPVM VSNVAYGRTI YVKLETTSKS 
301:	KDVQAAFKAL LKDNSVETSG QYKDIFEEST FTAVVLGGDA KEHNKVVTKD FNEIRNIIKD 
361:	NAELSLKNPA YPISYTSTFL KDNATAAVHN NTDYIETTTT EYSSAKMTLD HYGAYVAQFD 
421:	VSWDEFTFDQ KGNEVLTHKT WDGSGKDKTA HYSTVIPLPP NSKNIKIVAR ECTGLAWEWW 
481:	RTIINEQNVP LTNEIKVSIG GTTLYPTASI SH