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1.C.12.1.6
Ivanolysin

Accession Number:P31831
Protein Name:TACY aka ILO
Length:528
Molecular Weight:58542.00
Species:Listeria ivanovii [1638]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Secreted1
Substrate large molecules, small molecules

Cross database links:

Pfam: PF01289   

Gene Ontology

GO:0015485 F:cholesterol binding
GO:0019835 P:cytolysis
GO:0019836 P:hemolysis by symbiont of host erythrocytes
GO:0009405 P:pathogenesis

References (1)

[1] “Listeriolysin genes: complete sequence of ilo from Listeria ivanovii and of lso from Listeria seeligeri.”  Haas A.et.al.   1543752

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKKIMLLLMT LLLVSLPLAQ EAQADASVYS YQGIISHMAP PASPPAKPKT PVEKKNAAQI 
61:	DQYIQGLDYD KNNILVYDGE AVKNVPPKAG YKEGNQYIVV EKKKKSINQN NADIQVINSL 
121:	ASLTYPGALV KANSELVENQ PDVLPVKRDS VTLSIDLPGM VNHDNEIVVQ NATKSNINDG 
181:	VNTLVDRWNN KYSEEYPNIS AKIDYDQEMA YSESQLVAKF GAAFKAVNNS LNVNFGAISE 
241:	GKVQEEVINF KQIYYTVNVN EPTSPSRFFG KSVTKENLQA LGVNAENPPA YISSVAYGRD 
301:	IFVKLSTSSH STRVKAAFDT AFKGKSVKGD TELENIIQNA SFKAVIYGGS AKDEVEIIDG 
361:	DLSKLRDILK QGANFDKKNP GVPIAYTTNF LKDNQLAVVK NNSEYIETTS KAYSDGKINL 
421:	DHSGAYVARF NVTWDEVSYD ANGNEVVEHK KWSENDKDKL AHFTTSIYLP GNARNINIHA 
481:	KECTGLAWEW WRTVVDDRNL PLVKNRNVCI WGTTLYPAYS DTVDNPIK