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1.C.123.1.4
Gasdermin C of 508 aas.  The N-terminal moiety promotes pyroptosis. It may be acting by homooligomerizing within the membrane and forming pores (Ding et al. 2016).

Accession Number:Q9BYG8
Protein Name:Gasdermin-C
Length:508
Molecular Weight:57692.00
Species:Homo sapiens (Human) [9606]
Location1 / Topology2 / Orientation3: Cytoplasm1
Substrate Solutes

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MPSMLERISK NLVKEIGSKD LTPVKYLLSA TKLRQFVILR KKKDSRSSFW EQSDYVPVEF 
61:	SLNDILEPSS SVLETVVTGP FHFSDIMIQK HKADMGVNVG IEVSVSGEAS VDHGCSLEFQ 
121:	IVTIPSPNLE DFQKRKLLDP EPSFLKECRR RGDNLYVVTE AVELINNTVL YDSSSVNILG 
181:	KIALWITYGK GQGQGESLRV KKKALTLQKG MVMAYKRKQL VIKEKAILIS DDDEQRTFQD 
241:	EYEISEMVGY CAARSEGLLP SFHTISPTLF NASSNDMKLK PELFLTQQFL SGHLPKYEQV 
301:	HILPVGRIEE PFWQNFKHLQ EEVFQKIKTL AQLSKDVQDV MFYSILAMLR DRGALQDLMN 
361:	MLELDSSGHL DGPGGAILKK LQQDSNHAWF NPKDPILYLL EAIMVLSDFQ HDLLACSMEK 
421:	RILLQQQELV RSILEPNFRY PWSIPFTLKP ELLAPLQSEG LAITYGLLEE CGLRMELDNP 
481:	RSTWDVEAKM PLSALYGTLS LLQQLAEA