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1.C.13.1.1
Channel-forming leucocidin cytotoxin, CTX

Accession Number:P14608
Protein Name:CTX
Length:286
Molecular Weight:31681.00
Species:Pseudomonas aeruginosa [287]
Location1 / Topology2 / Orientation3: Secreted1
Substrate ions

Cross database links:

Gene Ontology

GO:0005576 C:extracellular region
GO:0009405 P:pathogenesis

References (3)

[1] “Pseudomonas aeruginosa cytotoxin: the nucleotide sequence of the gene and the mechanism of activation of the protoxin.”  Hayashi T.et.al.   2507866
[2] “The cytotoxin of Pseudomonas aeruginosa: cytotoxicity requires proteolytic activation.”  Orlik-Eisel G.et.al.   1695085
[3] “Purification and characterization of cytotoxin from the crude extract of Pseudomonas aeruginosa.”  Hayashi T.et.al.   2497292

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNDIDTITNA WGRWKTAQYG TTCWFTESTQ YGRNKDTRSY MQHQTNVSAP KDLVYSNFVQ 
61:	QDGGSTLLGQ YDMINEGSQV IELAVNLQQG LVDTFTWSVT EQLKVGVEVK VKANIPLVGG 
121:	AEITSTVELS LSSTQGASTS KSSNYGASTK VLISPHSHGW GEVALSFTEL RTQWVGNVGL 
181:	QGYVAIWFNN KVALNNDGDY HYLWFIPVEQ VFWECVQHNI VNTSGYVVQG NGVLAQATGT 
241:	FHSSVGLNLK TIAHERPYPE TSEAVRTFYN YASLVPDLET RVRSAE