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1.C.14.1.2
Cytohemolysin 1 precursor, Hly1

Accession Number:P55870
Protein Name:Hly1 aka AHH1
Length:621
Molecular Weight:68907.00
Species:Aeromonas hydrophila [380703]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Secreted1 / Multi-pass membrane protein2
Substrate ions

Cross database links:

eggNOG: NOG123668
HEGENOM: HBG739831
RefSeq: YP_856050.1   
Entrez Gene ID: 4487585   
Pfam: PF12563    PF07968    PF00652   
KEGG: aha:AHA_1512   

Gene Ontology

GO:0005576 C:extracellular region
GO:0005529 F:sugar binding
GO:0019835 P:cytolysis
GO:0019836 P:hemolysis by symbiont of host erythrocytes
GO:0009405 P:pathogenesis

References (2)

[1] “Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all trades.”  Seshadri R.et.al.   16980456
[2] “Nucleotide sequence and expression of an extracellular hemolysin gene of Aeromonas hydrophila.”  Hirono I.et.al.   1800890

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MKNKKPRKFI TQAPTLSLLA LALLAGSVQA EDIGERTDQG TAMLASLQSE QGLIYLNADV 
61:	WLKRQGATPL MTRDQLRERV LARGERLFID FSAVTDQSER QQTRKAMEQL AGISFDADWV 
121:	LVSGYKGELL FTPLGGVDDP AFYQVMERVE SLEGQGKRHK RSLTQPPAAE AGLPHVAFYL 
181:	NVNRKISDAE CTFPRSRTWS RGDRLFCDSP NISLVYRVNL ERSLQFGNTG SATPDAKIVR 
241:	ISLDEESAGA GIQLNEDLTW SENIADYLLL DGWARDYATD AIAQDYRFSI EASNTKAAVL 
301:	KSLPTNLNSK YEHREISGFE VGVTGGVEVN KDGPKAKLEA SAKFSQQRQL AYNTQDYRVE 
361:	RSAPSAQKVS FSWVRDQYAT AESLLSSKTA TVWGMGYDVD HNRIQPLSYK GFVPNLDVIY 
421:	KAAPDETGST EFKIDSSVNI RPIYTGIYKH YYVVGAHVSF QGFEDTDKRR RVTASTSFKV 
481:	DWNHPVFTGG RPVNLQLGGF DNRCLSADAN HGLSAVTCDE TSAAQSFIYD QYGRYVSAQD 
541:	TRRCLDGNNL GQLQSCSLSL GQRWEWKADS DALSNLSAHQ LLGHDKQSGA LGLYDENGNP 
601:	QNVSVRTLTS YTRIFGPPAS H