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1.C.14.1.3
Vibrio vulnificus hemolysin (VVH-A).  Consists of three domains:  Hemolysin N (residues 1 - 200), Leukocidin (residues 220 - 480) and Ricin (690 - 600).

Accession Number:P19247
Protein Name:Cytolysin
Length:471
Molecular Weight:52899.00
Species:Vibrio vulnificus [672]
Substrate ions

Cross database links:

HEGENOM: HBG265775
Entrez Gene ID: 1180412   
Pfam: PF07968    PF00652   
KEGG: vvu:VV2_0404   

Gene Ontology

GO:0005576 C:extracellular region
GO:0005529 F:sugar binding
GO:0019835 P:cytolysis
GO:0044179 P:hemolysis in other organism

References (1)

[1] “The cytolysin gene of Vibrio vulnificus: sequence and relationship to the Vibrio cholerae E1 Tor hemolysin gene.”  Yamamoto K.et.al.   2370116
Structure:
4OWJ   4OWK   4OWL     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MKKMTLFTLS LLATAVQVGA QEYVPIVEKP IYITSSKIKC VLHTSGDFNA TRDWCNAGAS 
61:	IDVRVNVAQM RSVQSATSDG FTPDAKIVRF TVDADKPGTG IHLVNELQQD HSWFQSWANR 
121:	RTYIGPFASS YDLWVKPVSG YTPKKARDLP QNENKNYQHR DTYGYSIGIN GKVGAEVNKD 
181:	GPKVGGEVSG SFTYNYSKTL VFDTKDYRIN NRSSLSDFDI SFEREFGECD ELRRQELGCY 
241:	FTAAHWGSGW VFDKTKFNPI SYSNFKPNYD VLYEAPVSET GVTDFEMGVK LNYRARFGTV 
301:	LPSALFSVYG SAGSSTNSST VKQRIRIDWN HPLFEAEAHV TLQSLSNNDL CLDVYGENGD 
361:	KTVAGGSVNG WSCHGSWNQV WGLDKEERYR SRVASDRCLT VNADKTLTVE QCGANLAQKW 
421:	YWEGDKLISR YVDGNNTRYL LNIVGGRNVQ VTPENEANQA RWKPTLQQVK L