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1.C.15.1.1
Putative porin TT95 (WSP)

Accession Number:O44397
Protein Name:TT95 aka WSP
Length:903
Molecular Weight:95690.00
Species:Trichuris trichiura [36087]
Location1 / Topology2 / Orientation3: Secreted1 / Multi-pass membrane protein2
Substrate small molecules

Cross database links:

Pfam: PF00095   

Gene Ontology

GO:0005576 C:extracellular region
GO:0030414 F:peptidase inhibitor activity

References (2)

[1] “The major secreted product of the whipworm, Trichuris, is a pore-forming protein.”  Drake L.et.al.   7991635
[2] “Isolation of a gene family that encodes the porin-like proteins from the human parasitic nematode Trichuris trichiura.”  Barker G.C.et.al.   10095112

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTAPGPLLIG LAICLLQGIQ DAESAKMGRC PPPSFGAGRA RFCYTDRQCP GRMKCCLTKR 
61:	GYACTAPDIS YPGPLKPTWN NPKCDEHGDC SKPKPQPADK QKPGTCPPSN MFTGTAPFCD 
121:	TDSDCKGIEK CCLTKAGHQC VQPVNGTVSR TKPGSCPPSP LGPVGLALFC QTDIDCEGSM 
181:	KCCMTIVGYE CTPPQKESDK SNKPGECPLA PAITGKALFC RSDNDCDGSE KCCFTKVGKE 
241:	CVKPIEKPRP VAKKGLCPPR PIGPVGLANF CQSDYDCDGS MKCCLTGIGY DCKAPVEEIE 
301:	EVNKTGLCPP TPAITGKALF CRKDNDCDGS EKCCFTEVGK ECVKPIEETK PIVKKGSCPP 
361:	KPNGPVGLAN FCQTDYDCDG SKKCCLTSIG YDCKAPVQES EEVQKPGSCP AAPAITGKAL 
421:	FCRTDKDCDG SEKCCFTKVG KECVQPADEP KPIAKKGSCP PAPVGPVGLA SFCQNDYDCD 
481:	GSKKCCLTSI GYDCKAPVQE SEEVQKPGSC PAAPAITGKA LFCRTDKDCD GSEKCCFTKV 
541:	GKECVQPADE PKPIAKKGSC PPAPVGPVGL ASFCQNDYDC DGSKKCCLTS IGYDCKAPVQ 
601:	ESEEVQKPGS CPAAPAITGK ALFCRTDKDC DGSEKCCFTK VGKECVQPAD EPKPIAKKGS 
661:	CPPAPVGPVG LASFCQNDYD CDGSKKCCLT SIGYDCKAPV QESEEVQKPG SCPAAPAMTG 
721:	KALFCRSDND CDGREKCCTT KVGKECVKPV RWPGPNAKPG SCPPSPGGAV GLASFCQSDF 
781:	DCMGYQKCCI TSARYECTNP VDENVRPSRR GICPWPYPVR LPVRACSIDD DCEESQKCCP 
841:	TKAGSACIIP VSEEMASGRV SCPPAVYVMF LRDSCRRDED CDDGKKCCDG NGRKSCSVLV 
901:	QRS