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1.C.19.1.2
Corticostatin III precursor

Accession Number:P01376
Protein Name:DEF3
Length:95
Molecular Weight:10460.00
Species:Oryctolagus cuniculus (Rabbit) [9986]
Location1 / Topology2 / Orientation3: Secreted1
Substrate small molecules, electrolytes, water

Cross database links:

RefSeq: NP_001164486.1   
Entrez Gene ID: 100009115   
Pfam: PF00323    PF00879   

Gene Ontology

GO:0005615 C:extracellular space
GO:0042742 P:defense response to bacterium
GO:0050832 P:defense response to fungus
GO:0031640 P:killing of cells of another organism
GO:0009615 P:response to virus

References (4)

[1] “The structure of the rabbit macrophage defensin genes and their organ-specific expression.”  Ganz T.et.al.   2745983
[2] “Primary structures of MCP-1 and MCP-2, natural peptide antibiotics of rabbit lung macrophages.”  Selsted M.E.et.al.   6643497
[3] “Primary structures of six antimicrobial peptides of rabbit peritoneal neutrophils.”  Selsted M.E.et.al.   3988726
[4] “Isolation and mode of action of rabbit corticostatic (antiadrenocorticotropin) peptides.”  Zhu Q.et.al.   1311240

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MRTLALLAAI LLVALQAQAE HVSVSIDEVV DQQPPQAEDQ DVAIYVKEHE SSALEALGVK 
61:	AGVVCACRRA LCLPRERRAG FCRIRGRIHP LCCRR