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1.C.19.1.4
Cryptdin-10 precursor (Cl- permeable)

Accession Number:P50708
Protein Name:DEFA aka DEFCR10
Length:93
Molecular Weight:10429.00
Species:Mus musculus (Mouse) [10090]
Location1 / Topology2 / Orientation3: Secreted1
Substrate Cl-

Cross database links:

Genevestigator: P50708
HEGENOM: HBG283450
Pfam: PF00323    PF00879   

Gene Ontology

GO:0005615 C:extracellular space
GO:0042742 P:defense response to bacterium

References (2)

[1] “Mouse Paneth cell defensins: primary structures and antibacterial activities of numerous cryptdin isoforms.”  Ouellette A.J.et.al.   7927786
[2] “Structure and diversity of the murine cryptdin gene family.”  Huttner K.M.et.al.   8188287

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MKTLVLLSAL VLLAFQVQAD PIQNTDEETK TEEQPGEDDQ AVSVSFGDPE GSSLQEESLR 
61:	DLVCYCRKRG CKGRERMNGT CRKGHLLYTM CCR