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1.C.21.1.1
Class I lantibiotic bacteriocin Lacticin 481

Accession Number:P36499
Protein Name:LAN4 aka LCTA aka LCT aka LCNDR1
Length:51
Molecular Weight:5677.00
Species:Lactococcus lactis (subsp [1360]
Location1 / Topology2 / Orientation3: Secreted1
Substrate small molecules, electrolytes, water

Cross database links:

Pfam: PF04604   

Gene Ontology

GO:0005576 C:extracellular region
GO:0005102 F:receptor binding
GO:0019835 P:cytolysis
GO:0042742 P:defense response to bacterium
GO:0019748 P:secondary metabolic process

References (4)

[1] “Structure, organization, and expression of the lct gene for lacticin 481, a novel lantibiotic produced by Lactococcus lactis.”  Piard J.-C.et.al.   8344922
[2] “Cloning, expression, and nucleotide sequence of genes involved in production of lactococcin DR, a bacteriocin from Lactococcus lactis subsp. lactis.”  Rince A.et.al.   8017945
[3] “Purification and partial characterization of lacticin 481, a lanthionine-containing bacteriocin produced by Lactococcus lactis subsp. lactis CNRZ 481.”  Piard J.-C.et.al.   16348628
[4] “The structure of the lantibiotic lacticin 481 produced by Lactococcus lactis: location of the thioether bridges.”  van den Hooven H.W.et.al.   8764998

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKEQNSFNLL QEVTESELDL ILGAKGGSGV IHTISHECNM NSWQFVFTCC S