TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.C.28.1.1
Cyclic bacteriocin, enterocin AS-48, Group I (105 aas; 2 TMSs) (van Belkum et al., 2011) (x-ray structure known (1O82_A))

Accession Number:Q47765
Protein Name:AS-48
Length:105
Molecular Weight:11076.00
Species:Enterococcus faecalis (Streptococcus faecalis) [1351]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Secreted1
Substrate small molecules, electrolytes, water

Cross database links:

Pfam: PF09221   

References (3)

[1] “Determination of the gene sequence and the molecular structure of the enterococcal peptide antibiotic AS-48.”  Martinez-Bueno M.et.al.   7929005
[2] “The cyclic structure of the enterococcal peptide antibiotic AS-48.”  Samyn B.et.al.   7925951
[3] “Analysis of the gene cluster involved in production and immunity of the peptide antibiotic AS-48 in Enterococcus faecalis.”  Martinez-Bueno M.et.al.   9484890
Structure:
1E68   1O82   1O83   1O84   4RGD     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MVKENKFSKI FILMALSFLG LALFSASLQF LPIAHMAKEF GIPAAVAGTV LNVVEAGGWV 
61:	TTIVSILTAV GSGGLSLLAA AGRESIKAYL KKEIKKKGKR AVIAW