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1.C.33.1.8
Cathelicidin-B1; reported to be processed, and the mature C-terminal active peptide is localized to the basolateral surface of M cells where it protects against bacterial infection (Goitsuka et al., 2007).

Accession Number:Q5F378
Protein Name:Cathelicidin-B1
Length:251
Molecular Weight:26927.00
Species:Gallus gallus (Chicken) [9031]
Location1 / Topology2 / Orientation3: Secreted1
Substrate small molecules

Cross database links:

Pfam: PF00666   

Gene Ontology

GO:0005576 C:extracellular region
GO:0042742 P:defense response to bacterium
GO:0045087 P:innate immune response

References (2)

[1] “Chicken cathelicidin-B1, an antimicrobial guardian at the mucosal M cell gateway.”  Goitsuka R.et.al.   17827276
[2] “Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.”  Caldwell R.B.et.al.   15642098

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MGRMWASEVL LLLLLGSSRA VTPGLDVSTA PGLDGSIPPG LDGSVSPGLD GSVSPGLDGS 
61:	ASPGLDGSVS PGLDGSASPG LDGSTPAGRD GTITPKLEGT ITPKQDGSIS PSWPWRWPIT 
121:	YLDAILAAVR LLNQKISGPC ILRLREAQPR PGWVGTLQRR REVSFLVEDG PCPPGVDCRS 
181:	CEPGALQHCV GTVSIEQQPT AELRCRPLRP QPIRNWWIRI WEWLNGIRKR LRQRSPFYVR 
241:	GHLNVTSTPQ P