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1.C.35.1.1
Amoebapore A

Accession Number:P34095
Protein Name:PFPA
Length:98
Molecular Weight:10504.00
Species:Entamoeba histolytica [5759]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cytoplasmic granule1
Substrate small molecules

Cross database links:

Pfam: PF05184    PF03489   

Gene Ontology

GO:0042742 P:defense response to bacterium
GO:0006629 P:lipid metabolic process

References (4)

[1] “Primary and secondary structure of the pore-forming peptide of pathogenic Entamoeba histolytica.”  Leippe M.et.al.   1396552
[2] “Unusual gene organization in the protozoan parasite Entamoeba histolytica.”  Bruchhaus I.et.al.   8274224
[3] “Pore-forming peptide of pathogenic Entamoeba histolytica.”  Leippe M.et.al.   1881907
[4] “Amoebapores, a family of membranolytic peptides from cytoplasmic granules of Entamoeba histolytica: isolation, primary structure, and pore formation in bacterial cytoplasmic membranes.”  Leippe M.et.al.   7715451
Structure:
1OF9     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MKAIVFVLIF AVAFAVTATH QGEILCNLCT GLINTLENLL TTKGADKVKD YISSLCNKAS 
61:	GFIATLCTKV LDFGIDKLIQ LIEDKVDANA ICAKIHAC