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1.C.38.1.12
Fragaceatoxin C (FraC), an alpha-barrel pore-forming protein, a cytolytic actinoporin, of 152 aas (Morante et al. 2015; Rojko et al. 2015).  Pore formation goes through a dimer intermediate and then generates the active octamer. Disrupting the key hydrophobic interaction between V60 and F163 (FraC numbering scheme) in the oligomerization interface of FraC, equinatoxin II (EqtII) and sticholysin II (StII) impairs the pore formation activity (Mesa-Galloso et al. 2016).

Accession Number:V9LHR3
Protein Name:Fragaceatoxin C
Length:152
Molecular Weight:16872.00
Species:Callorhynchus milii (Elephant fish) [7868]
Substrate small molecules

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  • 2° Structure (Network Protein Sequence Analysis)

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FASTA formatted sequence
1:	HFKLSLPATY AYCGRVNIPP DPTIEKGQKG VSVFIKTPLS AYGCVGVLSY MFDDQQISLL 
61:	FSNPLDQLKY NVEYALYIPD QTTPTDEALY NNMYYHLSET KSFTKASLGR GNATLQIVTD 
121:	QMEVTATMAN EKSKAIIKLQ VGDASSTPFR PN