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1.C.47.1.1
Defensin precursor

Accession Number:P36192
Protein Name:DEFI aka DEF aka CG1385
Length:92
Molecular Weight:10190.00
Species:Drosophila melanogaster (Fruit fly) [7227]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Secreted1
Substrate small molecules, ions

Cross database links:

eggNOG: inNOG11761
RefSeq: NP_523672.1   
Entrez Gene ID: 36047   
Pfam: PF01097   
BioCyc: DMEL-XXX-02:DMEL-XXX-02-003770-MONOMER   
KEGG: dme:Dmel_CG1385   

Gene Ontology

GO:0005615 C:extracellular space
GO:0019731 P:antibacterial humoral response
GO:0050830 P:defense response to Gram-positive bacterium
GO:0045087 P:innate immune response

References (4)

[1] “Characterization and transcriptional profiles of a Drosophila gene encoding an insect defensin. A study in insect immunity.”  Dimarcq J.-L.et.al.   8168509
[2] “Molecular population genetics of inducible antibacterial peptide genes in Drosophila melanogaster.”  Lazzaro B.P.et.al.   12716986
[3] “The genome sequence of Drosophila melanogaster.”  Adams M.D.et.al.   10731132
[4] “Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.”  Misra S.et.al.   12537572

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKFFVLVAIA FALLACVAQA QPVSDVDPIP EDHVLVHEDA HQEVLQHSRQ KRATCDLLSK 
61:	WNWNHTACAG HCIAKGFKGG YCNDKAVCVC RN