TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.C.51.1.1
Pilosulin (Philosin I) (from MyrPI)

Accession Number:Q07932
Protein Name:MYR1
Length:112
Molecular Weight:11849.00
Species:Myrmecia pilosula (Bulldog ant) (Australian jumper ant) [13618]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Secreted1
Substrate ions

Cross database links:

Gene Ontology

GO:0005576 C:extracellular region
GO:0019835 P:cytolysis
GO:0042742 P:defense response to bacterium
GO:0050832 P:defense response to fungus
GO:0019836 P:hemolysis by symbiont of host erythrocytes

References (8)

[1] “Molecular cloning and characterization of a major allergen (Myr p I) from the venom of the Australian jumper ant, Myrmecia pilosula.”  Donovan G.R.et.al.   7678752
[2] “Expression of jumper ant (Myrmecia pilosula) venom allergens: post-translational processing of allergen gene products.”  Donovan G.R.et.al.   8866004
[3] “Characterisation of major peptides in 'jack jumper' ant venom by mass spectrometry.”  Davies N.W.et.al.   15019477
[4] “Molecular cloning and characterization of the major allergen Myr p II from the venom of the jumper ant Myrmecia pilosula: Myr p I and Myr p II share a common protein leader sequence.”  Street M.D.et.al.   8605256
[5] “Cytotoxicity of pilosulin 1, a peptide from the venom of the jumper ant Myrmecia pilosula.”  Wu Q.-X.et.al.   9813247
[6] “Flow cytometric analysis of cell killing by the jumper ant venom peptide pilosulin 1.”  King M.A.et.al.   9701394
[7] “Identification and optimization of an antimicrobial peptide from the ant venom toxin pilosulin.”  Zelezetsky I.et.al.   15639237
[8] “Identification of an IgE-binding determinant of the major allergen Myr p I from the venom of the Australian jumper ant Myrmecia pilosula.”  Donovan G.R.et.al.   7508264

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MKLSCLLLTL TIIFVLTIVH APNVEAKDLA DPESEAVGFA DAFGEADAVG EADPNAGLGS 
61:	VFGRLARILG RVIPKVAKKL GPKVAKVLPK VMKEAIPMAV EMAKSQEEQQ PQ