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1.C.57.1.3
Lethal toxin

Accession Number:Q46342
Protein Name:Cytotoxin L
Length:2364
Molecular Weight:270580.00
Species:Clostridium sordellii [1505]
Location1 / Topology2 / Orientation3: Mitochondrion inner membrane1
Substrate peptides, small molecules

Cross database links:

Pfam: PF01473    PF04488    PF11713   

References (2)

[1] “Cloning and characterization of the cytotoxin L-encoding gene of Clostridium sordellii: homology with Clostridium difficile cytotoxin B.”  Green G.A.et.al.   7642137
[2] “Characterisation of an enterotoxin-negative, cytotoxin-positive strain of Clostridium sordellii.”  Green G.A.et.al.   8544213
Structure:
2VKD   2VKH   2VL8     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNLVNKAQLQ KMVYVKFRIQ EDEYVAILNA LEEYHNMSES SVVEKYLKLK DINNLTDNYL 
61:	NTYKKSGRNK ALKKFKEYLT MEVLELKNNS LTPVEKNLHF IWIGGQINDT AINYINQWKD 
121:	VNSDYTVKVF YDSNAFLINT LKKTIVESAT NNTLESFREN LNDPEFDYNK FYRKRMEIIY 
181:	DKQKHFIDYY KSQIEENPEF IIDNIIKTYL SNEYSKDLEA LNKYIEESLN KITANNGNDI 
241:	RNLEKFADED LVRLYNQELV ERWNLAAASD ILRISMLKED GGVYLDVDIL PGIQPDLFKS 
301:	INKPDSITNT SWEMIKLEAI MKYKEYIPGY TSKNFDMLDE EVQRSFESAL SSKSDKSEIF 
361:	LPLDDIKVSP LEVKIAFANN SVINQALISL KDSYCSDLVI NQIKNRYKIL NDNLNPSINE 
421:	GTDFNTTMKI FSDKLASISN EDNMMFMIKI TNYLKVGFAP DVRSTINLSG PGVYTGAYQD 
481:	LLMFKDNSTN IHLLEPELRN FEFPKTKISQ LTEQEITSLW SFNQARAKSQ FEEYKKGYFE 
541:	GALGEDDNLD FAQNTVLDKD YVSKKILSSM KTRNKEYIHY IVQLQGDKIS YEASCNLFSK 
601:	DPYSSILYQK NIEGSETAYY YYVADAEIKE IDKYRIPYQI SNKRNIKLTF IGHGKSEFNT 
661:	DTFANLDVDS LSSEIETILN LAKADISPKY IEINLLGCNM FSYSISAEET YPGKLLLKIK 
721:	DRVSELMPSI SQDSITVSAN QYEVRINEEG KREILDHSGK WINKEESIIK DISSKEYISF 
781:	NPKENKIIVK SKYLHELSTL LQEIRNNANS SDIDLEKKVM LTECEINVAS NIDRQIVEGR 
841:	IEEAKNLTSD SINYIKNEFK LIESISDSLY DLKHQNGLDD SHFISFEDIS KTENGFRIRF 
901:	INKETGNSIF IETEKEIFSE YATHISKEIS NIKDTIFDNV NGKLVKKVNL DAAHEVNTLN 
961:	SAFFIQSLIE YNTTKESLSN LSVAMKVQVY AQLFSTGLNT ITDASKVVEL VSTALDETID 
1021:	LLPTLSEGLP IIATIIDGVS LGAAIKELSE TNDPLLRQEI EAKIGIMAVN LTAASTAIVT 
1081:	SALGIASGFS ILLVPLAGIS AGIPSLVNNE LILQDKATKV IDYFKHISLA ETEGAFTLLD 
1141:	DKIIMPQDDL VLSEIDFNNN SITLGKCEIW RAEGGSGHTL TDDIDHFFSS PSITYRKPWL 
1201:	SIYDVLNIKK EKIDFSKDLM VLPNAPNRVF GYEMGWTPGF RSLDNDGTKL LDRIRDHYEG 
1261:	QFYWRYFAFI ADALITKLKP RYEDTNVRIN LDGNTRSFIV PVITTEQIRK NLSYSFYGSG 
1321:	GSYSLSLSPY NMNIDLNLVE NDTWVIDVDN VVKNITIESD EIQKGELIEN ILSKLNIEDN 
1381:	KIILNNHTIN FYGDINESNR FISLTFSILE DINIIIEIDL VSKSYKILLS GNCMKLIENS 
1441:	SDIQQKIDHI GFNGEHQKYI PYSYIDNETK YNGFIDYSKK EGLFTAEFSN ESIIRNIYMP 
1501:	DSNNLFIYSS KDLKDIRIIN KGDVKLLIGN YFKDDMKVSL SFTIEDTNTI KLNGVYLDEN 
1561:	GVAQILKFMN NAKSALNTSN SLMNFLESIN IKNIFYNNLD PNIEFILDTN FIISGSNSIG 
1621:	QFELICDKDK NIQPYFINFK IKETSYTLYV GNRQNLIVEP SYHLDDSGNI SSTVINFSQK 
1681:	YLYGIDRYVN KVIIAPNLYT DEINITPVYK PNYICPEVII LDANYINEKI NVNINDLSIR 
1741:	YVWDNDGSDL ILIANSEEDN QPQVKIRFVN VFKSDTAADK LSFNFSDKQD VSVSKIISTF 
1801:	SLAAYSDGFF DYEFGLVSLD NDYFYINSFG NMVSGLIYIN DSLYYFKPPK NNLITGFTTI 
1861:	DGNKYYFDPT KSGAASIGEI TIDGKDYYFN KQGILQVGVI NTSDGLKYFA PAGTLDENLE 
1921:	GESVNFIGKL NIDGKIYYFE DNYRAAVEWK LLDDETYYFN PKTGEALKGL HQIGDNKYYF 
1981:	DDNGIMQTGF ITINDKVFYF NNDGVMQVGY IEVNGKYFYF GKNGERQLGV FNTPDGFKFF 
2041:	GPKDDDLGTE EGELTLYNGI LNFNGKIYFF DISNTAVVGW GTLDDGSTYY FDDNRAEACI 
2101:	GLTVINDCKY YFDDNGIRQL GFITINDNIF YFSESGKIEL GYQNINGNYF YIDESGLVLI 
2161:	GVFDTPDGYK YFAPLNTVND NIYGQAVKYS GLVRVNEDVY YFGETYKIET GWIENETDKY 
2221:	YFDPETKKAY KGINVVDDIK YYFDENGIMR TGLISFENNN YYFNEDGKMQ FGYLNIKDKM 
2281:	FYFGKDGKMQ IGVFNTPDGF KYFAHQNTLD ENFEGESINY TGWLDLDGKR YYFTDEYIAA 
2341:	TGSLTIDGYN YYFDPDTAEL VVSE