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1.C.57.1.4
α-toxin

Accession Number:Q46149
Protein Name:Alpha-Toxin
Length:2178
Molecular Weight:250136.00
Species:Clostridium novyi [1542]
Location1 / Topology2 / Orientation3: Mitochondrion inner membrane1
Substrate peptides, small molecules

Cross database links:

Pfam: PF04488    PF11713   

References (1)

[1] “Sequencing and analysis of the gene encoding the alpha-toxin of Clostridium novyi proves its homology to toxins A and B of Clostridium difficile.”  Hofmann F.et.al.   7616958
Structure:
2VK9     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MLITREQLMK IASIPLKRKE PEYNLILDAL ENFNRDIEGT SVKEIYSKLS KLNELVDNYQ 
61:	TKYPSSGRNL ALENFRDSLY SELRELIKNS RTSTIASKNL SFIWIGGPIS DQSLEYYNMW 
121:	KMFNKDYNIR LFYDKNSLLV NTLKTAIIQE SSKVIIEQNQ SNILDGTYGH NKFYSDRMKL 
181:	IYRYKRELKM LYENMKQNNS VDDIIINFLS NYFKYDIGKL NNQKENNNNK MIAIGATDIN 
241:	TENILTNKLK SYYYQELIQT NNLAAASDIL RIAILKKYGG VYCDLDFLPG VNLSLFNDIS 
301:	KPNGMDSNYW EAAIFEAIAN EKKLMNNYPY KYMEQVPSEI KERILSFVRN HDINDLILPL 
361:	GDIKISQLEI LLSRLKAATG KKTFSNAFII SNNDSLTLNN LISQLENRYE ILNSIIQEKF 
421:	KICETYDSYI NSVSELVLET TPKNLSMDGS SFYQQIIGYL SSGFKPEVNS TVFFSGPNIY 
481:	SSATCDTYHF IKNTFDMLSS QNQEIFEASN NLYFSKTHDE FKSSWLLRSN IAEKEFQKLI 
541:	KTYIGRTLNY EDGLNFNKWK RVTTSELLKV IEEVNSTKIY ENYDLNMILQ IQGDDISYES 
601:	AVNVFGKNPN KSILIQGVDD FANVFYFENG IVQSDNINNI LSRFNDIKKI KLTLIGHGEN 
661:	VFNPKLFGGK TVNDLYTNII KPKLQHLLER EGVILKNKYL KINILGCYMF TPKVDINSTF 
721:	VGKLFNKISR DLQPKGFSKN QLEISANKYA IRINREGKRE VLDYFGKWVS NTDLIAEQIS 
781:	NKYVVYWNEV ENTLSARVEQ LNKVAEFAKD INSIIQTTNN QELKQSLVNT YADLITTLYS 
841:	ELLKEDIPFE LDNIQIKERI ILNEISRLHD FSNIILDFYQ KNNISNNMII LFDSIIKEKD 
901:	YYNVKLANKI TGETSVIKTY SDSLWNFTNK YKKIVDDIKG IIVKDINGEF IKKADFEIEQ 
961:	NPSLLNSAML MQLLIDYKPY TEILTNMNTS LKVQAYAQIF QLSIGAIQEA TEIVTIISDA 
1021:	LNANFNILSK LKVGSSVASV IIDGINLIAA LTELKNVKTN FERKLIEAKV GMYSIGFILE 
1081:	SSSLISGLLG ATAVSEILGV ISVPVAGILV GLPSLVNNIL VLGEKYNQIL DYFSKFYPIV 
1141:	GKNPFSIQDN IIIPYDDIAI TELNFKYNKF KYGYAKISGL KVGLVTHIGE NIDHYFSAPS 
1201:	LDHYIELSIY PALKLNDTNL PKGNVVLLPS GLNKVYKPEI SAIAGANSQE GNGVEVLNLI 
1261:	RNYYVDSNGN TKFPWKYEAP FEYSFSYMRV EYFDTKVNVI LDNENKTLII PVLTIDEMRN 
1321:	KISYEILGDG GQYNVILPVN QTNINIVSNK NDIWNFDVSY IVKESKIEDN KFVLDGFINN 
1381:	IFSTLKVSND GFKIGKQFIS IKNTPRAINL SFKINNNIVI VSIYLNHEKS NSITIISSDL 
1441:	NDIKNNFDNL LDNINYIGLG SISDNTINCI VRNDEVYMEG KIFLNEKKLV FIQNELELHL 
1501:	YDSVNKDSQY LINNPINNVV KYKDGYIVEG TFLINSTENK YSLYIENNKI MLKGLYLESS 
1561:	VFKTIQDKIY SKEKVNDYIL SLIKKFFTVN IQLCPFMIVS GVDENNRYLE YMLSTNNKWI 
1621:	INGGYWENDF NNYKIVDFEK CNVIVSGSNK LNSEGDLADT IDVLDKDLEN LYIDSVIIIP 
1681:	KVYTKKIIIH PIPNNPQINI INTQSIHDKC HLIIDSVLTN NYHWESDGDD LIITNGLDIN 
1741:	IRILQGLSFG FKYKNIYLKF SNYDELSLND FLLQNYNVKG LYYINGELHY KNIPGDTFEY 
1801:	GWINIDSRWY FFDSINLIAK KGYQEIEGER YYFNPNTGVQ ESGVFLTPNG LEYFTNKHAS 
1861:	SKRWGRAINY TGWLTLDGNK YYFQSNSKAV TGLQKISDKY YYFNDNGQMQ IKWQIINNNK 
1921:	YYFDGNTGEA IIGWFNNNKE RYYFDSEGRL LTGYQVIGDK SYYFSDNING NWEEGSGVLK 
1981:	SGIFKTPSGF KLFSSEGDKS AINYKGWLDL NGNKYYFNSD SIAVTGSYNI KGIQYYFNPK 
2041:	TAVLTNGWYT LDNNNYYVSN GHNVLGYQDI DGKGYYFDPS TGIQKAGVFP TPNGLRYFTM 
2101:	KPIDGQRWGQ CIDYTGWLHL NGNKYYFGYY NSAVTGWRVL GGKRYFFNIK TGAATTGLLT 
2161:	LSGKRYYFNE KGEQLTLV