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1.C.57.3.3
Cytotoxic necrotizing factor type 2, Cnf2 (Oswald et al., 1994)

Accession Number:Q47107
Protein Name:Cnf2 aka Cytotoxic necrotizing factor type 2
Length:1014
Molecular Weight:114660.00
Species:Escherichia coli [562]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Cytoplasm1 / Single-pass membrane protein2
Substrate peptides, small molecules

Cross database links:

Pfam: PF05785   

References (1)

[1] “Cytotoxic necrotizing factor type 2 produced by virulent Escherichia coli modifies the small GTP-binding proteins Rho involved in assembly of actin stress fibers.”  Oswald E.et.al.   8170993

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNVQWQQKYL LEYNELVSNF PSPERVVSDY IRRCFKTDLP WFSQVDPDNT YFIRFSQSRS 
61:	NSRSYTGWDH LGKYKTGVLT LTQAALINIG YHFDVFDDAN ASAGIYKTSS ADMFNEKNEE 
121:	KMLPSEYLYF LKGCDFSGIY GRFLSDYWSK YYDKFKLLLK NYYISSALYL YKNGEIDEYE 
181:	YNFSISALNR RDNISLFFFD IYGYYSSDMF VAKNNERVML FIPGAKKPFL FEKNIADLRI 
241:	SLKNLIKEND NKQLLSQHFS LYSRQDGITY AGVNSVLNAI ENDGVFNESY FLYSNKRINN 
301:	KDVFDAVAFS VKKRSFSDGD IVIKSNSEAQ RDYALTILQT ILSMTPIFDV AIPEVSVTLG 
361:	LGIIASSMGI SFDQLINGDT YEERRSAIPG LATNAALLGL SFAIPFLISK AGTNQKILSR 
421:	YTKHEIRTLN ETNIDMFLEE YGINKNSISE TKVLEVELKG SGQHVNIVKL SDEDNKIVAV 
481:	KGNSLSGIYY EVDIETGYEI SSRRIYRTEY NDKIFWTRGG GLKGGQSFDF ESLKLPIFFK 
541:	DEPYSAVPGS SLSFINDDSS LLYPNSTPKL PQPTPEMEIV NYVKRAGNFG ERLVTLMRGT 
601:	TEEEAWNIAR YHTAGGSTEE LHEILLGQGP QSSLGFTEYT SNINSADAAS RRHFLVVIKV 
661:	QVKYINNNNV SHVNHWAIPD EAPVEVLAVV DRRFNFPEPS TPPNISIIHK LLSLRYFKEN 
721:	IESTSRLNLQ KLNRGNIDIF KGRGSISSTR QRAIYPYFES ANADEQQPVF FYIKKNRFDD 
781:	FGYDQYFYNS TVGLNGIPTL NTYTGEILSD ASSLGSTYWK KYNLTNETSI IRVSNSARGA 
841:	NGIKIALEEV QEGKPVIITS GNLSGCTTIV ARKGGYLYKV HTGTTIPLAG FTSTTGVKKA 
901:	VEVFELLTNN PMPRVEGVMN NDFLVNYLAE SFDESLITYS SSEQKIGSKI TISRDNVSTF 
961:	PYFLDNIPEK GFGTSVTILV RVDGNVIVKS LSESYSLNVE NSNISVLHVF SKDF