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1.C.6.1.1
M1-1 protoxin precursor killer toxin K1

Accession Number:P01546
Protein Name:M11P aka YKT-K1
Length:316
Molecular Weight:34826.00
Species:Saccharomyces cerevisiae virus M1 (ScV-M1) [12450]
Number of TMSs:3
Location1 / Topology2 / Orientation3: Secreted1 / Multi-pass membrane protein2
Substrate ions

Cross database links:

RefSeq: NP_044402.1   
Entrez Gene ID: 1494398   

Gene Ontology

GO:0033644 C:host cell membrane
GO:0016021 C:integral to membrane
GO:0005529 F:sugar binding
GO:0009405 P:pathogenesis

References (5)

[1] “Sequence of the preprotoxin dsRNA gene of type I killer yeast: multiple processing events produce a two-component toxin.”  Bostian K.A.et.al.   6697395
[2] “Cloning and sequencing of the preprotoxin-coding region of the yeast M1 double-stranded RNA.”  Skipper N.et.al.   6368221
[3] “Cloning, sequencing and expression of a full-length cDNA copy of the M1 double-stranded RNA virus from the yeast, Saccharomyces cerevisiae.”  Russell P.J.et.al.   9234671
[4] “Yeast K1 killer toxin forms ion channels in sensitive yeast spheroplasts and in artificial liposomes.”  Martinac B.et.al.   1696721
[5] “Viral induced yeast apoptosis.”  Schmitt M.J.et.al.   18291112

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTKPTQVLVR SVSILFFITL LHLVVALNDV AGPAETAPVS LLPREAPWYD KIWEVKDWLL 
61:	QRATDGNWGK SITWGSFVAS DAGVVIFGIN VCKNCVGERK DDISTDCGKQ TLALLVSIFV 
121:	AVTSGHHLIW GGNRPVSQSD PNGATVARRD ISTVADGDIP LDFSALNDIL NEHGISILPA 
181:	NASQYVKRSD TAEHTTSFVV TNNYTSLHTD LIHHGNGTYT TFTTPHIPAV AKRYVYPMCE 
241:	HGIKASYCMA LNDAMVSANG NLYGLAEKLF SEDEGQWETN YYKLYWSTGQ WIMSMKFIEE 
301:	SIDNANNDFE GCDTGH