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1.C.67.1.1
The pore-forming hemolysin, SphH

Accession Number:O34095
Protein Name:SphH
Length:554
Molecular Weight:64433.00
Species:Leptospira interrogans serovar lai [57678]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate small molecules, large molecules

Cross database links:

Pfam: PF03372   

Gene Ontology

GO:0005576 C:extracellular region
GO:0008081 F:phosphoric diester hydrolase activity

References (1)

[1] “Identification and partial characterization of a novel hemolysin from Leptospira interrogans serovar lai.”  Lee S.H.et.al.   10974532

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MRNIFRKKNN GIRNTYKKSK SLIGFYCLFM FFLNCLPDKQ KEHADLLMSL LLFSKDQNIQ 
61:	FANISAERIG IDAQVSSEVD IKILSYNLFM YHKGLFNSGN WGQEKRARLL VDSKYVKDQD 
121:	VLVLEGVFDT KSKNILMNGL RSQYPNQIDV IGRATYGWNQ TLGDFRAFPL DNDYNGGVIV 
181:	LSKWPIEEKI QYIFENHGCG NDYYYNKGFV YVKINKHGRK YHIIGTDVQN TSCSDLGQNA 
241:	RKHQFVEIKN FINLKQVPKN ETIFLAGSFN VNKGSTEYQD ILMILGVDEP HYAGISFTWD 
301:	PKKNAIASYT SGTNQVSSYL EYIFVVGTHF KPQVWQNLAY DPITPTTWNV VGYTGYEFSD 
361:	RYPVYGFTYA DSNTPTQSAH RRKYDQVSFE SMSTGKKIQA DPKQANGWLQ VNASDETEFT 
421:	KFNLLQEADP KSDTNCLKSG YTRIEPSYYL NYYWNWWLGG GKGNYAYYPK FNDASNNLQI 
481:	HVLDEEECIK DGSRIVFKDY DGATLDYYYL TIWDGGNWDG YLYLWNKTYN LRETFKVRLN 
541:	TKPERDWKDD LIYR