1.C.77.1.2 β-synuclein of 134 aas. The expression of β-synuclein can be regulated by Ca2+-dependent protein kinase G (PKG)-activation via stimulation of
NMDA receptors (TC# 1.A.10) and voltage-operated Ca2+ channels (TC# 1.A.1) in the endoplasmic
reticulum in the dorsal striatum (Yang and Choe 2014). Also forms a complex with the Slick/Slack channel, presumably to regulate its channel activity (Rizzi et al. 2015).
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Accession Number: | Q16143 |
Protein Name: | Beta-synuclein |
Length: | 134 |
Molecular Weight: | 14288.00 |
Species: | Homo sapiens (Human) [9606] |
Location1 / Topology2 / Orientation3: |
Cytoplasm1 |
Substrate |
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1: MDVFMKGLSM AKEGVVAAAE KTKQGVTEAA EKTKEGVLYV GSKTREGVVQ GVASVAEKTK
61: EQASHLGGAV FSGAGNIAAA TGLVKREEFP TDLKPEEVAQ EAAEEPLIEP LMEPEGESYE
121: DPPQEEYQEY EPEA