TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.C.97.3.3
Aegerolysin (135aas) (Homologous to Pleurotolysin A).  Aegerolysin-like proteins provide the membrane cholesterol/sphingomyelin selectivity and recruit oligomerized pleurotolysin B molecules to create a membrane-inserted pore complex (Ota et al. 2014).

Accession Number:D2QTE8
Protein Name:Aegerolysin
Length:135
Molecular Weight:14983.00
Species:Spirosoma linguale (strain ATCC 33905 / DSM 74 / LMG 10896) [504472]
Substrate cholesterol, Sphingomyelin

Cross database links:

Entrez Gene ID: 8729899   
Pfam: PF06355   
KEGG: sli:Slin_6118    sli:Slin_6118   

Gene Ontology

GO:0030582 P:fruiting body development
GO:0019836 P:hemolysis by symbiont of host erythrocytes

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MAYSEWVEIR IYSENMEIKI KNIKLNWGKF YEGPNQDIEI TAPVLSDAVI KSGEKYTVWS 
61:	CGRDGASSGT EGSFELYDGD TQVARFGWIC PWSGANSCSL IPGEQENKLY KTARQWSGLT 
121:	SGPLGTITLS CVKLL