TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.E.10.1.1
Lysis holin protein (late protein GP14) (Tedin et al. 1995).

Accession Number:P11188
Protein Name:VG14 aka GP14 aka 14
Length:131
Molecular Weight:15032.00
Species:Bacteriophage phi-29 [10756]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Host membrane1 / Single-pass membrane protein2
Substrate endolysin

Cross database links:

RefSeq: YP_002004543.1   
Entrez Gene ID: 6446519   
Pfam: PF05105   

Gene Ontology

GO:0016998 P:cell wall macromolecule catabolic process
GO:0019835 P:cytolysis

References (2)

[1] “Nucleotide sequence of the late region of Bacillus phage phi 29 completes the 19,285-bp sequence of phi 29 genome. Comparison with the homologous sequence of phage PZA.”  Vlcek C.et.al.   3803926
[2] “Nucleotide sequence of Bacillus phage phi 29 genes 14 and 15: homology of gene 15 with other phage lysozymes.”  Garvey K.J.et.al.   3027653

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MKMIAWMQHF LETDETKLIY WLTFLMVCMV VDTVLGVLFA KLNPNIKFSS FKIKTGVLIK 
61:	VSEMILALLA IPFAVPFPAG LPLLYTVYTA LCVSEIYSIF GHLRLVDDKS DFLEILENFF 
121:	KRTSGKNKEE K