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1.E.16.1.1
Cph1 holin (Functionally characterized (Martín et al. 1998)).

Accession Number:Q38008
Protein Name:Cph1 aka 21
Length:134
Molecular Weight:15510.00
Species:Bacteriophage Cp-1 [10747]
Number of TMSs:3
Location1 / Topology2 / Orientation3: Host membrane1 / Multi-pass membrane protein2
Substrate endolysin

Cross database links:

RefSeq: NP_044836.1   
Entrez Gene ID: 1261217   
Pfam: PF05105   

Gene Ontology

GO:0033644 C:host cell membrane
GO:0016021 C:integral to membrane
GO:0016998 P:cell wall macromolecule catabolic process
GO:0019835 P:cytolysis

References (2)

[1] “Analysis of the complete nucleotide sequence and functional organization of the genome of Streptococcus pneumoniae bacteriophage Cp-1.”  Martin A.C.et.al.   8648702
[2] “Functional analysis of the two-gene lysis system of the pneumococcal phage Cp-1 in homologous and heterologous host cells.”  Martin A.C.et.al.   9440507

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MLYNIMLEVA KGDYITILFA LILFDFITGF LKAWKWKVTD SWTGLKGVIK HTLTFIFYYF 
61:	VAVFLTYIHA MAVGQILLVI INLYYALSIM ENLAVMGVFI PKFMTARVQE ELQKYTAQLD 
121:	AGKDLLEEFK GEKK