1.G.2 The Viral Pore-forming Membrance Fusion Protein-2 (VMFP2) Family
Like the Influenza HA protein, the Paramyxovirus F protein is of Class I (White et al. 2008) and shares the characteristics noted in the description for family 1.H.1. It is the second best charaterized Class I viral fusion protein. The crystal structures of various ectodomains are known. The F protein consists of three domains, domains, I, II, and III (Lamb and Jardetzky, 2007).