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1.N.2.1.1
Myomaker (Tmem8c) of 221 aas and 7 TMSs.  Myoblast-specific protein that mediates myoblast fusion, an essential step for the formation of multi-nucleated muscle fibers. It actively participates in the membrane fusion reaction (Schejter 2016). Fusion is dependent on the fusogenic peptide, myomixer (Bi et al. 2017).  Myomaker is required for stem cell fusion in skeletal muscle (Goh and Millay 2017).

Accession Number:A6NI61
Protein Name:Protein myomaker
Length:221
Molecular Weight:24699.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate small molecules

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MGTLVAKLLL PTLSSLAFLP TVSIAAKRRF HMEAMVYLFT LFFVALHHAC NGPGLSVLCF 
61:	MRHDILEYFS VYGTALSMWV SLMALADFDE PKRSTFVMFG VLTIAVRIYH DRWGYGVYSG 
121:	PIGTAILIIA AKWLQKMKEK KGLYPDKSVY TQQIGPGLCF GALALMLRFF FEDWDYTYVH 
181:	SFYHCALAMS FVLLLPKVNK KAGSPGTPAK LDCSTLCCAC V