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1.b.1.1.2
PhoE phosphoporin. The 3-d structure is available (PDB#1PHO)

Accession Number:P02932
Protein Name:PhoE aka OMPE aka B0241
Length:351
Molecular Weight:38922.00
Species:Escherichia coli [83333]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell outer membrane1 / Multi-pass membrane protein2
Substrate phosphate

Cross database links:

Genevestigator: P02932
EchoBASE: EB0722
EcoGene: EG10729
eggNOG: COG3203
HEGENOM: HBG673855
DIP: DIP-10498N
RefSeq: AP_000894.1    NP_414776.1   
Entrez Gene ID: 944926   
Pfam: PF00267   
BioCyc: EcoCyc:MONOMER0-282    ECOL168927:B0241-MONOMER   
KEGG: ecj:JW0231    eco:b0241   

Gene Ontology

GO:0009279 C:cell outer membrane
GO:0005886 C:plasma membrane
GO:0046930 C:pore complex
GO:0005215 F:transporter activity
GO:0006811 P:ion transport
GO:0006950 P:response to stress

References (8)

[1] “Complete nucleotide sequence of phoE, the structural gene for the phosphate limitation inducible outer membrane pore protein of Escherichia coli K12.”  Overbeeke N.et.al.   6341601
[2] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[3] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[4] “Analysis of the Escherichia coli proBA locus by DNA and protein sequencing.”  Deutch A.H.et.al.   6089111
[5] “Carboxy-terminal phenylalanine is essential for the correct assembly of a bacterial outer membrane protein.”  Struyve M.et.al.   1848301
[6] “Structural architecture of an outer membrane channel as determined by electron crystallography.”  Jap B.K.et.al.   1848682
[7] “Crystal structures explain functional properties of two E. coli porins.”  Cowan S.W.et.al.   1380671
[8] “Topology of PhoE porin: the 'eyelet' region.”  Struyve M.et.al.   7679770
Structure:
1PHO     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKKSTLALVV MGIVASASVQ AAEIYNKDGN KLDVYGKVKA MHYMSDNASK DGDQSYIRFG 
61:	FKGETQINDQ LTGYGRWEAE FAGNKAESDT AQQKTRLAFA GLKYKDLGSF DYGRNLGALY 
121:	DVEAWTDMFP EFGGDSSAQT DNFMTKRASG LATYRNTDFF GVIDGLNLTL QYQGKNENRD 
181:	VKKQNGDGFG TSLTYDFGGS DFAISGAYTN SDRTNEQNLQ SRGTGKRAEA WATGLKYDAN 
241:	NIYLATFYSE TRKMTPITGG FANKTQNFEA VAQYQFDFGL RPSLGYVLSK GKDIEGIGDE 
301:	DLVNYIDVGA TYYFNKNMSA FVDYKINQLD SDNKLNINND DIVAVGMTYQ F