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2.A.1.1.10
Maltotriose/maltose:H+ symporter, Mal6T or Mal61 (Dietvorst et al. 2005).  The orthologue (90% identical) in Saccharomyces pastorianus (Lager yeast) (Saccharomyces cerevisiae x Saccharomyces eubayanus), MTT1 or Mty1 of 615 aas, has higher affinity for maltotriose than maltose (Magalhães et al. 2016).

Accession Number:P15685
Protein Name:MA6T aka MAL6 aka MAL6T aka MAL61
Length:614
Molecular Weight:68226.00
Species:Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate H+, Xylose

Cross database links:

Genevestigator: P15685
Pfam: PF00083   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0022891 F:substrate-specific transmembrane transporte...
GO:0008643 P:carbohydrate transport
GO:0000023 P:maltose metabolic process
GO:0055085 P:transmembrane transport

References (3)

[1] “Primary structure of the maltose-permease-encoding gene of Saccharomyces carlsbergensis.”  Yao B.et.al.   2507395
[2] “The maltose permease encoded by the MAL61 gene of Saccharomyces cerevisiae exhibits both sequence and structural homology to other sugar transporters.”  Cheng Q.et.al.   2689282
[3] “Primary structure of the maltase gene of the MAL6 locus of Saccharomyces carlsbergensis.”  Hong S.H.et.al.   3516795

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKGLSSLINR KKDRNDSHLD EIENGVNATE FNSIEMEEQG KKSDFDLSHL EYGPGSLIPN 
61:	DNNEEVPDLL DEAMQDAKEA DESERGMPLM TALKTYPKAA AWSLLVSTTL IQEGYDTAIL 
121:	GAFYALPVFQ KKYGSLNSNT GDYEISVSWQ IGLCLCYMAG EIVGLQVTGP SVDYMGNRYT 
181:	LIMALFFLAA FIFILYFCKS LGMIAVGQAL CGMPWGCFQC LTVSYASEIC PLALRYYLTT 
241:	YSNLCWTFGQ LFAAGIMKNS QNKYANSELG YKLPFALQWI WPLPLAVGIF LAPESPWWLV 
301:	KKGRIDQARR SLERILSGKG PEKELLVSME LDKIKTTIEK EQKMSDEGTY WDCVKDGINR 
361:	RRTRIACLCW IGQCSCGASL IGYSTYFYEK AGVSTDTAFT FSIIQYCLGI AATFVSWWAS 
421:	KYCGRFDLYA FGLAFQAIMF FIIGGLGCSD THGAKMGSGA LLMVVAFFYN LGIAPVVFCL 
481:	VSEMPSSRLR TKTIILARNA YNVIQVVVTV LIMYQLNSEK WNWGAKSGFF WGGFCLATLA 
541:	WAVVDLPETA GRTFIEINEL FRLGVPARKF KSTKVDPFAA AKAAAAEINV KDPKEDLETS 
601:	VVDEGRSTPS VVNK