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2.A.1.1.105
Hexose transporter HXT11 (Low-affinity glucose transporter LGT3)

Accession Number:P54862
Protein Name:Hexose transporter HXT11
Length:567
Molecular Weight:62733.00
Species:Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Hexoses

Cross database links:

Genevestigator: P54862
eggNOG: COG0477
HEGENOM: HOG000202870
DIP: DIP-4071N
Entrez Gene ID: 854009   
Pfam: PF00083   
KEGG: sce:YOL156W   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005353 F:fructose transmembrane transporter activity
GO:0005354 F:galactose transmembrane transporter activity
GO:0005355 F:glucose transmembrane transporter activity
GO:0015578 F:mannose transmembrane transporter activity

References (3)

[1] “Analysis of the DNA sequence of a 15,500 bp fragment near the left telomere of chromosome XV from Saccharomyces cerevisiae reveals a putative sugar transporter, a carboxypeptidase homologue and two new open reading frames.”  Gamo F.-J.et.al.   8810044
[2] “The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.”  Dujon B.et.al.   9169874
[3] “A global topology map of the Saccharomyces cerevisiae membrane proteome.”  Kim H.et.al.   16847258

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSGVNNTSAN ELSTTMSNSN SAVGAPSVKT EHGDSKNSLN LDANEPPIDL PQKPLSAYTT 
61:	VAILCLMIAF GGFIFGWDTG TISGFVNLSD FIRRFGQKND KGTYYLSKVR MGLIVSIFNI 
121:	GCAIGGIVLS KVGDIYGRRI GLITVTAIYV VGILIQITSI NKWYQYFIGR IISGLGVGGI 
181:	AVLSPMLISE VAPKHIRGTL VQLYQLMGTM GIFLGYCTNY GTKNYHNATQ WRVGLGLCFA 
241:	WATFMVSGMM FVPESPRYLI EVGKDEEAKR SLSKSNKVSV DDPALLVEYD TIKAGIELEK 
301:	LAGNASWSEL LSTKTKVFQR VLMGVMIQSL QQLTGDNYFF YYGTTIFKSV GLKDSFQTSI 
361:	IIGVVNFFSS FIAVYTIERF GRRTCLLWGA ASMLCCFAVF ASVGVTKLWP QGSSHQDITS 
421:	QGAGNCMIVF TMFFIFSFAT TWAGGCYVIV SETFPLRVKS RGMAIATAAN WMWGFLISFF 
481:	TPFITGAINF YYGYVFLGCL VFAYFYVFFF VPETKGLTLE EVNTMWLEGV PAWKSASWVP 
541:	PERRTADYDA DAIDHDNRPI YKRFFSS