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2.A.1.1.129
High-capacity facilitative transporter for trehalose, TRET1, required to induce anhydrobiosis. Anhydrobiotic larvae can survive almost complete dehydration. Does not transport maltose, sucrose or lactose. Transports trehalose synthesized in the fat body and incorporates trehalose into other tissues that require a carbon source, thereby regulating trehalose levels in the hemolymph (Kikawada et al. 2007; Kanamori et al. 2010).  70% identical to the Drosophila homologue, TC# 2.a.1.1.99.

Accession Number:A5LGM7
Protein Name:Facilitated trehalose transporter Tret1
Length:504
Molecular Weight:55057.00
Species:Polypedilum vanderplanki (Sleeping chironomid) [319348]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Trehalose

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MELNNKEDSP RHTVPFVRQI TEDGKAKLEI YRPTTNPIYI YTQILAAIAV SMGSMVVGFA 
61:	SAYTSPALVS MQNTTITSFK VTEQEASWVG GIMPLAGLAG GIAGGPFIEY LGRKNTILAT 
121:	AVPFIVAWLL IAFANSIWMV LAGRALSGFC VGIASLSLPV YLGETVQPEV RGTLGLLPTA 
181:	FGNIGILICF VAGKYVNWSG LAFIGSILPI PFMVLTLLIP ETPRWFVTRG REERARKALQ 
241:	WLRGKKADVE PELKGIVKSH CEAERHASQN AIFDLMKRSN LKPLLIALGL MFFQQLSGIN 
301:	AVIFYTVSIF KDAGSTIDEN LCTIIVGVVN FGATFFATVL IDRLGRKILL YISEVAMVIT 
361:	LLTLGTFFYY KNSGNDVSNI GWLPLASFVI YVIGFSSGVG PIPWLMLGEI LPGKIRGSAA 
421:	SVATGFNWTC TFIVTKTFAD IVAAIGNHGA FWFFGVICLI GLFFVIFFVP ETQGKSLEEI 
481:	ERKMMGRVRR MSSVANMKPL SFNM