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2.A.1.1.16
Low-affinity hexose (glucose, fructose, mannose, 2-deoxyglucose) uniporter.  The evolution of hexose transporters in kinetoplastid protozoans has been studied (Pereira and Silber 2012).

Accession Number:Q01441
Protein Name:Gtr2 aka D2
Length:558
Molecular Weight:60216.00
Species:Leishmania donovani [5661]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Hexoses

Cross database links:

Pfam: PF00083   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0022891 F:substrate-specific transmembrane transporte...
GO:0008643 P:carbohydrate transport
GO:0055085 P:transmembrane transport

References (1)

[1] “Molecular characterization of two genes encoding members of the glucose transporter superfamily in the parasitic protozoan Leishmania donovani.”  Langford C.K.et.al.   1435876

External Searches:

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  • CDD Search (Conserved Domain Database)
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  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTLKKRSSAP ELPTSLDEDE EEDSPQPLSN TPFFSMKNLI VATPIILTPL LYGYNLGFVG 
61:	PYSTMYGYAS NCQLYSAKKS CETLTAAKCR WFNASTYVSN TTYGEVCGWA DRTTCFLKYS 
121:	DEAGCLSDSA CKWSYSANTC GNQVGYSSIQ SGVFAGSLVI GSTMGALMGG YLTKRLDYCK 
181:	SFLFIGLLSV IGNVLTHVAT GLFHYWVLFV ARIVLGFPLG WQSITSSHYT DKFAPANHAK 
241:	TLGTLFQVSV STGIFVTSFF GLVLGNTIQY DAASNANTMG RMQGLVSVST LLSIFVVFLP 
301:	LITKDGYSKS RRGDYEGENS EDASRKAAEE YTMTQMIGPI LNGVAMGCVT QLTGINANMN 
361:	FAPTIMSNLG LQPLVGNIIV MAWNMLATFC VIPLSRRFSM RTLFLFCGFV GSLCCVFLGG 
421:	IPVYPGVTKS DKAISGIAIT GIAIFIALYE MGVGPCFYVL AVDVFPESFR PIGSSITVGV 
481:	MFIFNLIINI CYPIATEGIS GGPSGNPNKG QAVAFIFFGC IGVVACVIEY FFLQPWVEPE 
541:	AKMTDDLDGA AVPEGKHD