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2.A.1.1.20
Myoinositol:H+ symporter, MIT

Accession Number:Q01440
Protein Name:GTR1 aka MIT
Length:547
Molecular Weight:58788.00
Species:Leishmania donovani [5661]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate myo-inositol

Cross database links:

Pfam: PF00083   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0022891 F:substrate-specific transmembrane transporte...
GO:0008643 P:carbohydrate transport
GO:0055085 P:transmembrane transport

References (1)

[1] “Molecular characterization of two genes encoding members of the glucose transporter superfamily in the parasitic protozoan Leishmania donovani.”  Langford C.K.et.al.   1435876

External Searches:

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  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MRASVMLCAA LGGFLFGYDT GVINAALFQM KDHFGFSEHS WQYALIVAIA IAGAFVGAFI 
61:	SGFISAAFGR RPCIAVADAL FVIGSVLMGA APNVEVVLVS RVIVGLAIGI SSATIPVYLA 
121:	EVTSPKHRGA TIVLNNLFLT GGQFVAAGFT AIMVVFTSKN IGWRVAIGIG ALPAVVQAFC 
181:	LLFFLPESPR WLLSKGHADR AKAVADKFEV DLCEFQEGDE LPSVRIDYRP LMARDMRFRV 
241:	VLSSGLQIIQ QFSGINTIMY YSSVILYDAG FRDAIMPVVL SIPLAFMNAL FTAVAIFTVD 
301:	RFGRRRMLLI SVFGCLVLLV VIAIIGFFIG TRISYSVGGG LFLALLAVFL ALYAPGIGCI 
361:	PWVIMGEIFP THLRTSAASV ATMANWGANV LVSQVFPILM GAIGVGGTFT IISGLMALGC 
421:	IFVYFFAVET KGLTLEQIDN MFRKRAGLPP RFHEEGESGE SGAGYREDGD LGRLATEDVC 
481:	DLSSLGNRVV SFAKAEDAFT EVAMPDRHAV SNKFEERATS SSSDPQSLEN QDEVRQAAIK 
541:	AAPHEPK