TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.1.1.22
Hexose:H+ symporter, Ght6 (Fructose > Glucose)

Accession Number:O74849
Protein Name:Ght6 aka MEU12 aka SPCC1235.13
Length:535
Molecular Weight:59404.00
Species:Schizosaccharomyces pombe (Fission yeast) [4896]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Hexose, H+

Cross database links:

eggNOG: fuNOG06406
HEGENOM: HBG744444
RefSeq: NP_587739.1   
Entrez Gene ID: 2538845   
Pfam: PF00083   
KEGG: spo:SPCC1235.13   

Gene Ontology

GO:0032153 C:cell division site
GO:0051286 C:cell tip
GO:0016021 C:integral to membrane
GO:0022891 F:substrate-specific transmembrane transporte...
GO:0007126 P:meiosis
GO:0055085 P:transmembrane transport

References (3)

[1] “Multiple hexose transporters of Schizosaccharomyces pombe.”  Heiland S.et.al.   10735857
[2] “The genome sequence of Schizosaccharomyces pombe.”  Wood V.et.al.   11859360
[3] “Comprehensive isolation of meiosis-specific genes identifies novel proteins and unusual non-coding transcripts in Schizosaccharomyces pombe.”  Watanabe T.et.al.   11376151

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MAKILTIVML VFVSMAGWMF GADTGSIGGI TNMRDFQSRY ADRYDPVTDT YSYSSARQGL 
61:	LVGMVNTGTT VGCLLSSPLG DRFGKRKCIM GWTLVYITGV IVQLTTIPSW VQMMVAKIWT 
121:	GLGIGALSVI APGYQSESSP PHIRGAIVTT YQLFITLGIF IAACINMGTH KYTTHPEAQW 
181:	RVPIGINLLW GILMFFGMLF LPESPRYLAV KGRNEECMKI LTRNAGLPAD HPIMQKEYNA 
241:	IQADVEAELA GGPCSWPQIF SNEIRYRTLL GMGVMAFQQL TGNNYFFYYG TQVFRGTGLN 
301:	SPFLAALILD AVNFGCTFGA IFVLEYFGRR GPLIVGGVWQ SICFFIYASV GDRALTRPNG 
361:	TSNHRAGAVM IVFSCLFIFS FAQTWAPAAY VIVGESYPIR YRSKCAAVAT ASNWFWNFMI 
421:	SFFTPFISNS IGFKYGYVFA ACNLCAAIII FLFAKETKGL TLEEINQLYL SNIKPWNTGA 
481:	YQRDREDIKQ SDSEKERGPT SKLHEYVEHA PNSYASTHST ESENYPQQVT NPVGL