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2.A.1.1.33
Fructose:H+ symporter, Frt1 (Diezemann and Boles, 2003)

Accession Number:Q8NJ22
Protein Name:Hexose transporter aka Frt1
Length:566
Molecular Weight:62763.00
Species:Kluyveromyces lactis (Yeast) [28985]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate fructose, H+

Cross database links:

eggNOG: fuNOG06413
HEGENOM: HBG325044
RefSeq: XP_454356.1   
Entrez Gene ID: 2893840   
Pfam: PF00083   
KEGG: kla:KLLA0E08987   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0022891 F:substrate-specific transmembrane transporte...
GO:0055085 P:transmembrane transport

References (2)

[1] “Functional characterization of the Frt1 sugar transporter and of fructose uptake in Kluyveromyces lactis.”  Diezemann A.et.al.   12677461
[2] “Genome evolution in yeasts.”  Dujon B.et.al.   15229592

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MSSNLSEKAV DQQKEFGLLK STSSVDSVHE VEAGVKVGED DDNYFFSEDQ ILTQIKVYED 
61:	EIANTPVTKT LRQRMRRMEF CEVNFSNKTY MVIMLGFFAS FAGILSGVDQ STISGASYGM 
121:	KASLKLTSDE DSLISSLMPL GAVGGSILLT PLSEYFGRKV ALVISCIFYT IGGILCAAAQ 
181:	DVHTMYAGRF LIGVGVGIEG GGVGVYIAES VPSTVRGSLV SLYQFNIALG ELVGYVIGVI 
241:	FFDVKGGWRY MLGSSLVFST ILFVGLFFLP ESPRWLIHKG YDVEAYKVWR RLRDTSDLGN 
301:	KREFLEMKHA AEQDRQLKEQ ESRFKSMFDL ILIPRNRRAL LYSIMMVSLG QLTGINAIMY 
361:	YMSTLMGQIG FSPKQAVAMS MVGGAALLIG TIPAILYMDK FGRRPWSMTI IGFSVGLVLV 
421:	GVGYQIDLNT NLAAAEGVYL TGQILYNIFF GTYATLTWVV PSESFSLATR SIGMTICSAF 
481:	LYLWAFTVTY NFNKMKDAFT YTGLTLGFYG GIAIVIGIPY QLLFMPETKD KTLEEIDDIF 
541:	EMPTRQLVKQ NLKNLKDYVS GNRKSI