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2.A.1.1.35
The major glucose (or 2-deoxyglucose) uptake transporter, GlcP (van Wezel et al., 2005)

Accession Number:Q7BEC4
Protein Name:GlcP
Length:472
Molecular Weight:50387.00
Species:Streptomyces lividans [1916]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate glucose

Cross database links:

Pfam: PF00083   

Gene Ontology

GO:0016020 C:membrane
GO:0022891 F:substrate-specific transmembrane transporte...
GO:0055085 P:transmembrane transport

References (1)

[1] “GlcP constitutes the major glucose uptake system of Streptomyces coelicolor A3(2).”  van Wezel G.P.et.al.   15659175

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MASTSQAPSP GAGTAHPDHL GHVIFIAAAA AMGGFLFGYD SSVINGAVEA IRDRYDVGSA 
61:	VLAQVIAVAL IGCAIGAATA GRIADRIGRI RCMQIAAVLF TVSAVGSALP FALWDLAMWR 
121:	IIGGFAIGMA SVIGPAYIAE VSPPAYRGRL GSFQQAAIVI GIAVSQLVNW GLLNAAGGDQ 
181:	RGELMGLEAW QVMLGVMVIP AVLYGLLSFA IPESPRFLIS VGKRERAKKI LEEVEGKDVD 
241:	FDARVTEIEH AMHREEKSSF KDLLGGSFFF KPIVWIGIGL SVFQQFVGIN VAFYYSSTLW 
301:	QSVGVDPADS FFYSFTTSII NIVGTVIAMI FVDRVGRKPL ALIGSVGMVI GLALEAWAFS 
361:	FDLVDGKLPA TQGWVALIAA HVFVLFFALS WGVVVWVFLG EMFPNRIRAA ALGVAASAQW 
421:	IANWAITASF PSLADWNLSG TYVIYTIFAA LSIPFVLKFV KETKGKALEE MG