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2.A.1.1.38
The glycerol:H+ symporter, Stl1p (Ferreira et al., 2005)

Accession Number:P39932
Protein Name:Stl1 aka YDR536W
Length:569
Molecular Weight:63532.00
Species:Saccharomyces cerevisiae (Baker's yeast) [4932]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate glycerol

Cross database links:

Genevestigator: P39932
eggNOG: fuNOG06168
HEGENOM: HBG330944
DIP: DIP-5275N
RefSeq: NP_010825.1   
Entrez Gene ID: 852149   
Pfam: PF00083   
KEGG: sce:YDR536W   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015295 F:solute:hydrogen symporter activity
GO:0015793 P:glycerol transport
GO:0055085 P:transmembrane transport

References (3)

[1] “The STL1 gene of Saccharomyces cerevisiae is predicted to encode a sugar transporter-like protein.”  Zhao S.et.al.   8076821
[2] “The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.”  Jacq C.et.al.   9169867
[3] “A global topology map of the Saccharomyces cerevisiae membrane proteome.”  Kim H.et.al.   16847258

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKDLKLSNFK GKFISRTSHW GLTGKKLRYF ITIASMTGFS LFGYDQGLMA SLITGKQFNY 
61:	EFPATKENGD HDRHATVVQG ATTSCYELGC FAGSLFVMFC GERIGRKPLI LMGSVITIIG 
121:	AVISTCAFRG YWALGQFIIG RVVTGVGTGL NTSTIPVWQS EMSKAENRGL LVNLEGSTIA 
181:	FGTMIAYWID FGLSYTNSSV QWRFPVSMQI VFALFLLAFM IKLPESPRWL ISQSRTEEAR 
241:	YLVGTLDDAD PNDEEVITEV AMLHDAVNRT KHEKHSLSSL FSRGRSQNLQ RALIAASTQF 
301:	FQQFTGCNAA IYYSTVLFNK TIKLDYRLSM IIGGVFATIY ALSTIGSFFL IEKLGRRKLF 
361:	LLGATGQAVS FTITFACLVK ENKENARGAA VGLFLFITFF GLSLLSLPWI YPPEIASMKV 
421:	RASTNAFSTC TNWLCNFAVV MFTPIFIGQS GWGCYLFFAV MNYLYIPVIF FFYPETAGRS 
481:	LEEIDIIFAK AYEDGTQPWR VANHLPKLSL QEVEDHANAL GSYDDEMEKE DFGEDRVEDT 
541:	YNQINGDNSS SSSNIKNEDT VNDKANFEG