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2.A.1.1.39
The high affinity glucose transporter, Hgt1 (Baruffini et al., 2006)

Accession Number:P49374
Protein Name:Hgt1 aka KLLA0A11110g
Length:551
Molecular Weight:60761.00
Species:Kluyveromyces lactis (Yeast) (Candida sphaerica) [28985]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate glucose

Cross database links:

eggNOG: fuNOG06221
HEGENOM: HBG744444
RefSeq: XP_451484.1   
Entrez Gene ID: 2896650   
Pfam: PF00083   
KEGG: kla:KLLA0A11110   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0022891 F:substrate-specific transmembrane transporte...
GO:0008643 P:carbohydrate transport
GO:0055085 P:transmembrane transport

References (2)

[1] “Glucose uptake in Kluyveromyces lactis: role of the HGT1 gene in glucose transport.”  Billard P.et.al.   8830679
[2] “Genome evolution in yeasts.”  Dujon B.et.al.   15229592

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MSLKNWLLLR DIQYEGTFYK KFPHVYNIYV IGFIACISGL MFGFDIASMS SMIGTDVYKD 
61:	YFSNPDSLTY GGITASMAGG SFLGSLISPN FSDAFGRKVS LHICAALWII GAILQCAAQD 
121:	QAMLIVGRVI SGMGIGFGSS AAPVYCSEIS PPKIRGTISG LFQFSVTVGI MVLFYIGYGC 
181:	HFIDGAAAFR ITWGLQMVPG LILMVGVFFI PESPRWLANH DRWEETSLIV ANIVANGDVN 
241:	NEQVRFQLEE IKEQVIIDSA AKNFGYKDLF RKKTLPKTIV GVSAQMWQQL CGMNVMMYYI 
301:	VYIFNMAGYT GNTNLVASSI QYVLNVVMTI PALFLIDKFG RRPVLIIGGI FMFTWLFSVA 
361:	GILATYSVPA PGGVNGDDTV TIQIPSENTS AANGVIASSY LFVCFFAPTW GIGIWIYCSE 
421:	IFNNMERAKG SALSAATNWA FNFALAMFVP SAFKNISWKT YIIFGVFSVA LTIQTFFMFP 
481:	ETKGKTLEEI DQMWVDNIPA WRTANYIPQL PIVKDEEGNK LGLLGNPQHL EDVHSNEKGL 
541:	LDRSDSASNS N