TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.1.1.45
Vacuolar (tonoplast) glucose transporter1, Vgt1 (important for seed germination and flowering) (Aluri and Büttner, 2007)

Accession Number:Q8L6Z8
Protein Name:D-xylose-proton symporter-like 1 aka VGT1
Length:503
Molecular Weight:53542.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate glucose

Cross database links:

Genevestigator: Q8L6Z8
eggNOG: KOG0254
HEGENOM: HBG744444
RefSeq: NP_186959.2   
Entrez Gene ID: 821117   
Pfam: PF00083   
KEGG: ath:AT3G03090   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0009705 C:plant-type vacuole membrane
GO:0005886 C:plasma membrane
GO:0005353 F:fructose transmembrane transporter activity
GO:0005355 F:glucose transmembrane transporter activity
GO:0015755 P:fructose transport
GO:0015758 P:glucose transport
GO:0009911 P:positive regulation of flower development
GO:0009624 P:response to nematode
GO:0009845 P:seed germination
GO:0055085 P:transmembrane transport

References (3)

[1] “Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.”  Salanoubat M.et.al.   11130713
[2] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[3] “The monosaccharide transporter gene family in land plants is ancient and shows differential subfamily expression and expansion across lineages.”  Johnson D.A.et.al.   16923188

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MGFDPENQSI SSVGQVVGDS SSGGITAEKE PLLKENHSPE NYSVLAAIPP FLFPALGALL 
61:	FGYEIGATSC AIMSLKSPTL SGISWYDLSS VDVGIITSGS LYGALIGSIV AFSVADIIGR 
121:	RKELILAAFL YLVGAIVTVV APVFSILIIG RVTYGMGIGL TMHAAPMYIA ETAPSQIRGR 
181:	MISLKEFSTV LGMVGGYGIG SLWITVISGW RYMYATILPF PVIMGTGMCW LPASPRWLLL 
241:	RALQGQGNGE NLQQAAIRSL CRLRGSVIAD SAAEQVNEIL AELSLVGEDK EATFGELFRG 
301:	KCLKALTIAG GLVLFQQITG QPSVLYYAPS ILQTAGFSAA ADATRISILL GLLKLVMTGV 
361:	SVIVIDRVGR RPLLLCGVSG MVISLFLLGS YYMFYKNVPA VAVAALLLYV GCYQLSFGPI 
421:	GWLMISEIFP LKLRGRGISL AVLVNFGANA LVTFAFSPLK ELLGAGILFC AFGVICVVSL 
481:	FFIYYIVPET KGLTLEEIEA KCL