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2.A.1.1.50
The glucose/fructose:H+ symporter, STP13 (sugar transport protein 13). Expressed in vascular tissues and induced during programmed cell death (Norholm et al., 2006).  Used to combat bacterial infection by competing with them for sugars by phosphorylation of STP13 by the BAK1 receptor kinase (Yamada et al. 2016).

Accession Number:Q94AZ2
Protein Name:Sugar transport protein 13 aka STP13
Length:526
Molecular Weight:57419.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate glucose, fructose, H+

Cross database links:

Genevestigator: Q94AZ2
eggNOG: KOG0254
HEGENOM: HBG744444
RefSeq: NP_198006.1   
Entrez Gene ID: 832703   
Pfam: PF00083   
KEGG: ath:AT5G26340   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005358 F:high-affinity hydrogen:glucose symporter ac...
GO:0008643 P:carbohydrate transport
GO:0055085 P:transmembrane transport

References (6)

[1] “Functional identification of an Arabidopsis Snf4 ortholog by screening for heterologous multicopy suppressors of snf4 deficiency in yeast.”  Kleinow T.et.al.   10929106
[2] “Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.”  Tabata S.et.al.   11130714
[3] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[4] “Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.”  Nuehse T.S.et.al.   14506206
[5] “Phosphoproteomics of the Arabidopsis plasma membrane and a new phosphorylation site database.”  Nuehse T.S.et.al.   15308754
[6] “The monosaccharide transporter gene family in land plants is ancient and shows differential subfamily expression and expansion across lineages.”  Johnson D.A.et.al.   16923188

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTGGGFATSA NGVEFEAKIT PIVIISCIMA ATGGLMFGYD VGVSGGVTSM PDFLEKFFPV 
61:	VYRKVVAGAD KDSNYCKYDN QGLQLFTSSL YLAGLTATFF ASYTTRTLGR RLTMLIAGVF 
121:	FIIGVALNAG AQDLAMLIAG RILLGCGVGF ANQAVPLFLS EIAPTRIRGG LNILFQLNVT 
181:	IGILFANLVN YGTAKIKGGW GWRLSLGLAG IPALLLTVGA LLVTETPNSL VERGRLDEGK 
241:	AVLRRIRGTD NVEPEFADLL EASRLAKEVK HPFRNLLQRR NRPQLVIAVA LQIFQQCTGI 
301:	NAIMFYAPVL FSTLGFGSDA SLYSAVVTGA VNVLSTLVSI YSVDKVGRRV LLLEAGVQMF 
361:	FSQVVIAIIL GVKVTDTSTN LSKGFAILVV VMICTYVAAF AWSWGPLGWL IPSETFPLET 
421:	RSAGQSVTVC VNLLFTFIIA QAFLSMLCHF KFGIFIFFSA WVLIMSVFVM FLLPETKNIP 
481:	IEEMTERVWK KHWFWARFMD DHNDHEFVNG EKSNGKSNGF DPSTRL