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2.A.1.1.53
Myo-Inositol uptake porter, IolT1 (Km=0.2mM) (Krings et al., 2006).  Can also transport D-glucose (Ikeda et al. 2011).

Accession Number:Q8NTX0
Protein Name:IolT1
Length:491
Molecular Weight:53171.00
Species:Corynebacterium glutamicum (Brevibacterium flavum) [1718]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate myo-inositol, glucose

Cross database links:

HEGENOM: HBG744444
RefSeq: NP_599433.1    YP_224478.1   
Entrez Gene ID: 1021246    3342898   
Pfam: PF00083   
BioCyc: CGLU196627:CG0223-MONOMER   
KEGG: cgb:cg0223    cgl:NCgl0178   

Gene Ontology

GO:0016020 C:membrane
GO:0022891 F:substrate-specific transmembrane transporte...
GO:0055085 P:transmembrane transport

References (1)

[1] “The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins.”  Kalinowski J.et.al.   12948626

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MASTFIQADS PEKSKKLPPL TEGPYRKRLF YVALVATFGG LLFGYDTGVI NGALNPMTRE 
61:	LGLTAFTEGV VTSSLLFGAA AGAMFFGRIS DNWGRRKTII SLAVAFFVGT MICVFAPSFA 
121:	VMVVGRVLLG LAVGGASTVV PVYLAELAPF EIRGSLAGRN ELMIVVGQLA AFVINAIIGN 
181:	VFGHHDGVWR YMLAIAAIPA IALFFGMLRV PESPRWLVER GRIDEARAVL ETIRPLERAH 
241:	AEVADVEHLA REEHAVSEKS MGLREILSSK WLVRILLVGI GLGVAQQLTG INSIMYYGQV 
301:	VLIEAGFSEN AALIANVAPG VIAVVGAFIA LWMMDRINRR TTLITGYSLT TISHVLIGIA 
361:	SVAFPVGDPL RPYVILTLVV VFVGSMQTFL NVATWVMLSE LFPLAMRGFA IGISVFFLWI 
421:	ANAFLGLFFP TIMEAVGLTG TFFMFAGIGV VALIFIYTQV PETRGRTLEE IDEDVTSGVI 
481:	FNKDIRKGKV H