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2.A.1.1.56
High affinity monosaccharide (KM ≈ 20 ┬ÁM):H+ symporter, Stp6 (takes up glucose, 3-O-methylglucose, mannose, fructose, galactose and to a lesser extent, xylose and ribulose. (Scholz-Starke et al., 2003)

Accession Number:Q9SFG0
Protein Name:Sugar transport protein 6 aka STP6
Length:507
Molecular Weight:55907.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate glucose, Sugars, 3-O-methylglucose, Mannose, fructose, Galactose, Xylose, Ribulose

Cross database links:

Genevestigator: Q9SFG0
eggNOG: KOG0254
HEGENOM: HBG744444
RefSeq: NP_187247.1   
Entrez Gene ID: 819766   
Pfam: PF00083   
KEGG: ath:AT3G05960   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015145 F:monosaccharide transmembrane transporter ac...
GO:0015293 F:symporter activity
GO:0034219 P:carbohydrate transmembrane transport

References (3)

[1] “AtSTP6, a new pollen-specific H(+)-monosaccharide symporter from Arabidopsis.”  Scholz-Starke J.et.al.   12529516
[2] “Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.”  Salanoubat M.et.al.   11130713
[3] “The monosaccharide transporter gene family in land plants is ancient and shows differential subfamily expression and expansion across lineages.”  Johnson D.A.et.al.   16923188

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MAVVVSNANA PAFEAKMTVY VFICVMIAAV GGLIFGYDIG ISGGVSAMDD FLKEFFPAVW 
61:	ERKKHVHENN YCKYDNQFLQ LFTSSLYLAA LVASFVASAT CSKLGRRPTM QFASIFFLIG 
121:	VGLTAGAVNL VMLIIGRLFL GFGVGFGNQA VPLFLSEIAP AQLRGGLNIV FQLMVTIGIL 
181:	IANIVNYFTA TVHPYGWRIA LGGAGIPAVI LLFGSLLIIE TPTSLIERNK NEEGKEALRK 
241:	IRGVDDINDE YESIVHACDI ASQVKDPYRK LLKPASRPPF IIGMLLQLFQ QFTGINAIMF 
301:	YAPVLFQTVG FGSDAALLSA VITGSINVLA TFVGIYLVDR TGRRFLLLQS SVHMLICQLI 
361:	IGIILAKDLG VTGTLGRPQA LVVVIFVCVY VMGFAWSWGP LGWLIPSETF PLETRSAGFA 
421:	VAVSCNMFFT FVIAQAFLSM LCGMRSGIFF FFSGWIIVMG LFAFFFIPET KGIAIDDMRE 
481:	SVWKPHWFWK RYMLPEDDHH DIEKRNA