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2.A.1.1.63
Low affinity inositol (myoinsoitol (Km = 1 mM), scylloinositol, d-chiroinositol and mucoinositol):H+ symporter (expressed in the anther tapetum, the vasculature, and the leaf mesophyll (Schneider et al., 2007)

Accession Number:Q9C757
Protein Name:INT2
Length:580
Molecular Weight:63449.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Myoinositol, Scylloinositol, d-chiroinositol, Mucoinositol, H+

Cross database links:

Genevestigator: Q9C757
eggNOG: KOG0254
HEGENOM: HBG744444
RefSeq: NP_174313.1   
Entrez Gene ID: 839902   
Pfam: PF00083   
KEGG: ath:AT1G30220   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0022891 F:substrate-specific transmembrane transporte...
GO:0015293 F:symporter activity
GO:0055085 P:transmembrane transport

References (4)

[1] “Arabidopsis INOSITOL TRANSPORTER4 mediates high-affinity H+ symport of myoinositol across the plasma membrane.”  Schneider S.et.al.   16603666
[2] “Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.”  Theologis A.et.al.   11130712
[3] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[4] “The monosaccharide transporter gene family in land plants is ancient and shows differential subfamily expression and expansion across lineages.”  Johnson D.A.et.al.   16923188

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MEGGIIHGGA DESAFKECFS LTWKNPYVLR LAFSAGIGGL LFGYDTGVIS GALLYIRDDF 
61:	KSVDRNTWLQ EMIVSMAVAG AIVGAAIGGW ANDKLGRRSA ILMADFLFLL GAIIMAAAPN 
121:	PSLLVVGRVF VGLGVGMASM TAPLYISEAS PAKIRGALVS TNGFLITGGQ FLSYLINLAF 
181:	TDVTGTWRWM LGIAGIPALL QFVLMFTLPE SPRWLYRKGR EEEAKAILRR IYSAEDVEQE 
241:	IRALKDSVET EILEEGSSEK INMIKLCKAK TVRRGLIAGV GLQVFQQFVG INTVMYYSPT 
301:	IVQLAGFASN RTALLLSLVT AGLNAFGSII SIYFIDRIGR KKLLIISLFG VIISLGILTG 
361:	VFYEAATHAP AISSLETQRF NNISCPDYKS AMNTNAWDCM TCLKASSPSC GYCSSPIGKE 
421:	HPGACWISDD SVKDLCHNEN RLWYTRGCPS NFGWFALLGL GLYIIFFSPG MGTVPWIVNS 
481:	EIYPLRFRGI CGGIAATANW ISNLIVAQSF LSLTEAIGTS WTFLIFGVIS VIALLFVMVC 
541:	VPETKGMPME EIEKMLERRS MEFKFWKKKS KLVEKQNQSA