TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.1.1.64
The hexose sensor, Hxs1 (believed to be non-transporting) (Stasyk et al., 2008)

Accession Number:B1PM37
Protein Name:Hxs1
Length:638
Molecular Weight:70536.00
Species:Pichia angusta (Yeast) (Hansenula polymorpha) [4905]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cytoplasmic vesicle1 / Multi-pass membrane protein2
Substrate Hexoses

Cross database links:

Pfam: PF00083   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0022891 F:substrate-specific transmembrane transporte...
GO:0055085 P:transmembrane transport

References (1)

[1] “Identification of hexose transporter-like sensor HXS1 and functional hexose transporter HXT1 in the methylotrophic yeast Hansenula polymorpha.”  Stasyk O.G.et.al.   18310355

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MSTEARDHSP PLELRDLSLQ EPAGCVEVRD TYTTTDYDQS AQPSVEDEKK DQAPDGAELE 
61:	CQRNWSSIMA VYVGLLMAIG GFLYGYDTGI INGLLEMKYV KRTFPPNNAG GFSASQSSII 
121:	TSVLSIGTFV GSLFAPVLSD RVGRRLSIVA SSTIMFSLGT ILQLVSEGIP LLCVGRFVSG 
181:	FGVGMISAII PLYQAEVSPK WIRGSVISFY QWAITWGLLV SSAITQATHS IDDARCYRIP 
241:	IGLQLIWGVV LGIGMYSLPE SPRFFVKKDR LDDALHALSR FRRLPLNDKS LVEELIEIKA 
301:	SHDYEMSFGP TSIMDCFRSS PSRASQLRRM LTGMLLQALQ QCSGINFIFY YGVNYFVRAG 
361:	IANSYLISFI TYTVNVVFTI PGIFSVEIWG RRWLLIVGAG GMTVSNFVIA AVGVTTDSLI 
421:	ANKVIVAFVC LFIAFFASTW GPLAWVVVGE MYSLSVRQKA VALTAATNWL VNFIFACCTP 
481:	YLVDTGKHTA ALGTKIFFLW GSLNFVGMVF AYFYIYETKG LLLEEVDELF RVCKSARKSM 
541:	YFKPHTETQE NEGSPRHSES HRANAVAMTL DILNVPNNVP PSVHSTDDES EFYHPHLSEY 
601:	LGPQPEYNYT NQEDLMGLIR SLGVGLDGTA ESVHSHGQ