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2.A.1.1.69
Sugar & polyol transporter 1 (SPT1): broad specificity; takes up glucose (Schilling and Oesterhelt, 2007). Loss of the first 3 TMSs of the 12 TMSs does not prevent sugar uptake or sugar recognition but lowers substrate affinity & transport rate, and abolished H+ symport (Schilling and Oesterhelt, 2007).

Accession Number:A1Z264
Protein Name:SPT1
Length:557
Molecular Weight:63415.00
Species:Galdieria sulphuraria GN=SPT1 PE=2 SV=1 [130081]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate glucose

Cross database links:

Pfam: PF00083   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0022891 F:substrate-specific transmembrane transporte...
GO:0055085 P:transmembrane transport

References (1)

[1] “Structurally reduced monosaccharide transporters in an evolutionarily conserved red alga.”  Schilling S.et.al.   17497961

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MEAITEFQQA AEPKNDLYDS TELQKEAGVT DLDDEYLTEE ERLHPWRQTR TFYWSVIVAS 
61:	VAVLFYGIDI TAISGAQVGY IPHFGLENRT YHQGVMVSCI YFGCFVGVFI ALFTNTYFGR 
121:	RFTISLASFI STGACIWEAV SPSWQVFIPG RIILGFSYGM IGETAPVYLA EMSPASIRGA 
181:	IVSLYQQVVT IGIFLAYLCN LIFVWVNYQN VGWRIMIGFP MVPSVIEMFL IWTVPESPRW 
241:	LIKRRRYEDA KRNLFKLRRT AETAERDFVR IKKGVEEDEI LQKGKNLLVE VIPVPYIRRA 
301:	LLIGIMEMLF QQMSGMNVFM NYIDEVFEEN INMGARTSVA VSLFPGFVNM VATVIVYFTI 
361:	DRYGRRTLQL VTFPVMFLML LMVLFSFYGD KKVNLAFFII GVVFFIVAYS PGAGPVPWTF 
421:	CAEVFPTYVR AAGTTITTFF VNAFNFALSF SWPSMKAAWG PQGGFGFYAG FNFLGIVMQF 
481:	LFLPETKGFT LEQMRVVFEE GLFTIAAYHC RAGWRSLRKL LGLSVPDTPL VSPYDKAFAI 
541:	DRAKREEEMM HAGEVSK