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2.A.1.1.71
Hexose (glucose) transporter, GT4 (D2) (almost identical to 2.A.1.1.16)

Accession Number:B1PLM1
Protein Name:Hexose transporter
Length:627
Molecular Weight:67607.00
Species:Leishmania mexicana [5665]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate glucose

Cross database links:

Pfam: PF00083   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0022891 F:substrate-specific transmembrane transporte...
GO:0055085 P:transmembrane transport

References (1)

[1] “Amplification of an alternate transporter gene suppresses the avirulent phenotype of glucose transporter null mutants in Leishmania mexicana.”  Feng X.et.al.   19017272

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MDSPNEKTRE DSCEPVHSLE VRGQVPAASA STSTTFTNRS PNEQPSNGKS TTQANAELPL 
61:	ISVAANSPSM TLRKRSSAPE LPTSLDEDED EDAPQPLPDA PFFSMKNLIV STPIILTPLL 
121:	YGYNLGFVGP YSTMYGYASN CQLYSAKRSC ETLAAAKCRW FNASTYVSNT TYGEVCGWAD 
181:	RTTCFLRYSD EASCLSHSAC KWSYSANTCG NQVGYSSIQS GVFAGSLVIG STIGALMGGY 
241:	LTKRLDYCKS FLFIGILSVI GNVLTHVATG LFHYWVLFLA RIVLGFPLGW QSITSSHYTD 
301:	KFAPANHAKT LGTLFQVSVS TGIFITSFFG LVLGNTIQYD AARNANTMGR MQGLVSVSTL 
361:	LSIFVVFLPL ITKDGYSKSR RGDYEEENSE DASRKAAEEY TMTQMIGPIL NGVAMGCVTQ 
421:	LTGINANMNF APTIMSNLGL QPLVGNIIVM AWNMLATFCV IPLSRRFSMR TLFLFCGFVG 
481:	SLCCVFLGGI PVYPGVTKSD KAVSGIAITG IAIFIALYEM GVGPCFYVLA VDVFPESFRP 
541:	IGSSITVGVM FIFNLIINIC YPIATEGISG GPSGNPNKGQ AVAFIFFGCI GVVACVIEYF 
601:	FLQPWEELEA KIADDLDGAA VPEGKHS