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2.A.1.1.77
The D-glucose/D-ribose transporter, LmGT2 (Most similar to 1.A.1.1.18) (Naula et al., 2010).

Accession Number:O61059
Protein Name:Glucose transporter
Length:567
Molecular Weight:61175.00
Species:Leishmania mexicana [5665]
Number of TMSs:12
Substrate D-glucose, D-ribose

Cross database links:

Pfam: PF00083   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0022891 F:substrate-specific transmembrane transporter activity
GO:0008643 P:carbohydrate transport

References (4)

[1] “Differential regulation of multiple glucose transporter genes in Leishmania mexicana.”  Burchmore R.J.et.al.   9786920
[2] “A glucose transporter can mediate ribose uptake: definition of residues that confer substrate specificity in a sugar transporter.”  Naula C.M.et.al.   20601430
[3] “Differential regulation of multiple glucose transporter genes in Leishmania mexicana.”  Burchmore R.J.et.al.   9786920
[4] “A glucose transporter can mediate ribose uptake: definition of residues that confer substrate specificity in a sugar transporter.”  Naula C.M.et.al.   20601430

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSDKLEANGR SSRSEKEPIH DVITKNVMED EDDAPPFLSA SNARVTLVQA IGGCLNGYSI 
61:	GFVGVYSTLF GYSTNCANFR SERGCTTAPN ADCQWFANAT GTSYCGWPEI TCRRTYTYSS 
121:	VAEMPGAIAQ CEADSRCRWS YSAKECQNPS GYSSSESGIF AGSMIAGCLI GSVFAGPLAS 
181:	TIGARLSFLL VGLVGVVSSV MCHVSASENE FWVLVVGRFV IGLFVGVIGV ACPVYTDQNA 
241:	HPKWKRTIGV MFQVFTTLGI FIAAAVGLAL GQSTYFDRNK DQMVMARMQG LCAFSTLFSL 
301:	LTILLGIVMS ESRAKFGGDD EEGGIELDPN EYSYVEMVPR LLMGAVMAGT LQLTGINAVM 
361:	NYAPAIMGSL GLAPLVGNFV VMLWNFVTTL ASIPLSYVFT MRQLFLFGSL FTSSMCLFMC 
421:	GIPVYPGVSK KTEVKNGVAI TGILLFILGF EVCVGPCYFV LTQDMFPLSF RPRGASFTQV 
481:	AQFIFNLIIN VCYPIATEHI SGGPSGNQDK GQAVAFIFFG CLGMICFIIQ VFFLHPWDEK 
541:	RDGKKRPATP AGGKRELSSS LSGNRAE