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2.A.1.1.90
Solute carrier family 2, facilitated glucose transporter member 14 (Glucose transporter type 14) (GLUT-14)

Accession Number:Q8TDB8
Protein Name:Solute carrier family 2, facilitated glucose transporter member 14
Length:520
Molecular Weight:56320.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate glucose

Cross database links:

Genevestigator: Q8TDB8
eggNOG: COG0477
HEGENOM: HOG000202871
Entrez Gene ID: 144195   
Pfam: PF00083   
KEGG: hsa:144195   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005355 F:glucose transmembrane transporter activity
GO:0030154 P:cell differentiation
GO:0015758 P:glucose transport
GO:0007275 P:multicellular organismal development
GO:0007283 P:spermatogenesis

References (4)

[1] “GLUT14, a duplicon of GLUT3, is specifically expressed in testis as alternative splice forms.”  Wu X.et.al.   12504846
[2] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[3] “The full-ORF clone resource of the German cDNA consortium.”  Bechtel S.et.al.   17974005
[4] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MEFHNGGHVS GIGGFLVSLT SRMKPHTLAV TPALIFAITV ATIGSFQFGY NTGVINAPET 
61:	IIKEFINKTL TDKANAPPSE VLLTNLWSLS VAIFSVGGMI GSFSVGLFVN RFGRRNSMLI 
121:	VNLLAATGGC LMGLCKIAES VEMLILGRLV IGLFCGLCTG FVPMYIGEIS PTALRGAFGT 
181:	LNQLGIVIGI LVAQIFGLEL ILGSEELWPV LLGFTILPAI LQSAALPCCP ESPRFLLINR 
241:	KKEENATRIL QRLWGTQDVS QDIQEMKDES ARMSQEKQVT VLELFRVSSY RQPIIISIVL 
301:	QLSQQLSGIN AVFYYSTGIF KDAGVQQPIY ATISAGVVNT IFTLLSLFLV ERAGRRTLHM 
361:	IGLGGMAFCS TLMTVSLLLK NHYNGMSFVC IGAILVFVAC FEIGPGPIPW FIVAELFSQG 
421:	PRPAAMAVAG CSNWTSNFLV GLLFPSAAYY LGAYVFIIFT GFLITFLAFT FFKVPETRGR 
481:	TFEDITRAFE GQAHGADRSG KDGVMGMNSI EPAKETTTNV